Question. I have read reports that antidepressants prescribed for patients in the depressed phase of cyclothymic or bipolar II illness can (a) shorten the cycles of the illness (b) possibly lead to refractory depression in the long run and (c) precipitate hypomanic episodes. Are you aware of any data on these issues? Do you know of any information on alteration of other aspects of the course of mild bipolar illness? ... Read More