54%–75% of adolescents "wish for more sleep" It is widely recognized that many older Americans suffer from a variety of sleep disorders. In fact, more than half of all Americans older than age 65 have a sleep problem, and disturbed sleep is among the most frequently cited problems affecting institutionalized older Americans. As the population ages, it is estimated that at the end of this decade nearly 80 million Americans will ... Read More

The American Psychiatric Association (1983) reports that recurrent episodes occur in at least 50% of patients who seek treatment for major depressive disorder (MDD). Most studies, though, have examined only single occurrences. To help describe the episodic nature of MDD, the National Institute of Mental Health initiated the Collaborative Program on the Psychobiology of Depression, a prospective, naturalistic, longitudinal investigation. This program's early research found the cumulative probability of recurrence ... Read More

Question. My patient is in the second trimester of her pregnancy. She has panic disorder and depression. In the past, she responded well to Zoloft and Klonopin. What are the safest medications for the next few months? Answer. The short, no-frills answer to your question is that any of the major antidepressants or anxiolytics are probably safe, now that the most vulnerable period of organ-formation (the first trimester) has passed. I ... Read More

Question. Do you have a list of drugs for depression, and non-addictive medications for anxiety? Tricyclics of the older vintage would be helpful. Answer. I am providing you with a list of commonly used antidepressants, as well as their usual doses: Maintenance Dosage and Tablet Size for Non-MAOI Antidepressants Antidepressant Tablet/capsule sizes Usual daily adult dose Amitriptyline (Elavil, Endep) 10, 25, 50, 75, 100, 150 mg 75-250 mg Amoxapine (Asendin) 25,50, 100, 150 mg 200-300 mg Bupropion (Wellbutrin) 75, 100 ... Read More