Tag archives for Serotonin
Serotonin
Posted By Kelly On Friday, January 1st 2010 under: Images Diagrams Tables Tags: Serotonin
The distribution in the human brain of neurons and their projections (arrows) containing serotonin. ... Read More
How are 5-HT2 selective antagonists different from current drug therapy in schizophrenia?
Posted By Kelly On Friday, December 11th 2009 under: Pharmacology Tags: Antidepressants, Drugs, Risperdal, Serotonin, Zyprexa
There a two major classes of agents currently used to treat schizophrenia - the older neuroleptics (typical antipsychotics) and the newer atypical antipsychotics such as clozapine, olanzapine (Zyprexa) and risperidone (Risperdal). The first class of agents is comprised of predominantly dopamine-2 (D2) receptor antagonists, with haloperidol being the prototype. These neuroleptics have little, if any, direct effects on serotonin systems; e.g., haloperidol does not interact appreciably with serotonin-2 (5-HT2) receptors. ... Read More
What is the role of serotonin in psychotic disorders?
Posted By Kelly On Thursday, December 10th 2009 under: Pharmacology Tags: Prozac, Psychiatric Illnesses, Serotonin
The precise role of serotonin (5-HT) in psychotic disorders is not fully understood. However, a variety of preclinical and clinical data suggest that 5-HT is closely connected with both psychotic symptoms and the mechanism of newer atypical antipsychotic agents. The serotonin-2A receptor (5-HT2A) in particular seems to play a pivotal role. For example, certain psychotomimetic substances, such as psilocybin, appear to act as agonists at the 5-HT2A receptor. Conversely, 5-HT2A ... Read More
