Tag archives for Selective serotonin reuptake inhibitors (SSRIs)
Antidepressants: Drug Interactions
Posted By Kelly On Sunday, June 27th 2010 under: Antidepressants Tags: MAOIs, Selective serotonin reuptake inhibitors (SSRIs), TCAs
The most common drug interaction with antidepressants is their influence on the metabolism of other drugs. Antidepressants are metabolized through catabolic enzymes located in a variety of places, but primarily in the smooth endoplasmic reticulum of hepatocytes: the cytochrome P450 (CYP) enzymes. Many other drugs are also metabolized through similar pathways: it is estimated that about half of all drugs prescribed depend on CYP for their metabolism.
Of these enzymes, most ... Read More
Antidepressants: Side Effects
Posted By Kelly On Wednesday, June 23rd 2010 under: Antidepressants Tags: Selective serotonin reuptake inhibitors (SSRIs), SNRIs, TCAs
Once the choice of an antidepressant has been made, the main goal is to maximize therapeutic effects and minimize side effects. Good preparation and reassurance of the patient is essential. Even relatively benign side effects are a major cause of treatment nonadherence; drop-out rates ranging from 7 to 44% have been reported in various studies of tricyclic antidepressants (TCAs), and from 7 to 23% in studies of serotonin reuptake inhibitors. ... Read More
Case: Antidepressant agents. Discussion
Posted By Kelly On Wednesday, June 2nd 2010 under: Pharmacotherapy Tags: Atypical Agents, Selective serotonin reuptake inhibitors (SSRIs), Tricyclic Agents
Class
Drugs used to treat depression are classified as TCAs, atypical heterocyclic (second- and third-generation) agents, SSRIs, and monoamine oxidase inhibitors (MAOIs). Other conditions for which certain antidepressant agents are used include panic disorder, obsessive-compulsive disease (OCD), bipolar affective disorder, chronic pain, and enuresis.
SSRIs are the most extensively prescribed antidepressant agents because, unlike tricyclic and heterocyclic agents, they produce less sedation, have fewer antimuscarinic cholinoreceptor effects, and are safer in overdose. ... Read More
Antidepressants as a Treatment for Bipolar Disorder
Posted By Kelly On Wednesday, January 13th 2010 under: Question - Answer Tags: Antidepressants, Bipolar disorder, Monoamine Oxidase Inhibitors (MAOIs), Selective serotonin reuptake inhibitors (SSRIs), Tricyclic Antidepressants (TCAs)
Question. I have read reports that antidepressants prescribed for patients in the depressed phase of cyclothymic or bipolar II illness can (a) shorten the cycles of the illness (b) possibly lead to refractory depression in the long run and (c) precipitate hypomanic episodes. Are you aware of any data on these issues? Do you know of any information on alteration of other aspects of the course of mild bipolar illness? ... Read More
Meds in the Second Trimester
Posted By Kelly On Tuesday, January 12th 2010 under: Question - Answer Tags: Anafranil, Antidepressants, Ativan, Benzodiazepines (BZDs), Buspar, Depression, Drugs, Effexor, Klonopin, Norpramin, Pamelor, Paxil, Pregnancy, Prozac, Selective serotonin reuptake inhibitors (SSRIs), Serzone, Tofranil, Valium, Zoloft
Question. My patient is in the second trimester of her pregnancy. She has panic disorder and depression. In the past, she responded well to Zoloft and Klonopin. What are the safest medications for the next few months?
Answer. The short, no-frills answer to your question is that any of the major antidepressants or anxiolytics are probably safe, now that the most vulnerable period of organ-formation (the first trimester) has passed. I ... Read More
What is the role of SSRIs in the treatment of social phobia?
Posted By Kelly On Thursday, December 17th 2009 under: Antidepressants Tags: Antidepressants, Drugs, Luvox, Prozac, Psychiatric Illnesses, Selective serotonin reuptake inhibitors (SSRIs), Zoloft
Social phobia has recently been recognized as a chronic and often debilitating disorder. It is estimated to affect up to 10% of the population, with onset occurring early in life.l According to the DSM-IV, in order to be diagnosed with social phobia individuals must meet several criteria. They must have a persistent fear of one or more social or performance situations where they are exposed to unfamiliar people or to ... Read More
Depression and Psychosis: Improving Outcomes
Posted By Kelly On Monday, December 14th 2009 under: Depression Tags: Antidepressants, Depression, Drugs, Psychosis, Selective serotonin reuptake inhibitors (SSRIs), Wellbutrin, Zyprexa
The following is the question and answer session from the Depression and Psychosis: Improving Outcomes. The presenters were Richard G. Petty, M.D., and Jack M. Gorman, M.D.
Question: What's the latest on quetiapine and slit lamp examinations?
Dr. Petty: As many of you will know, quetiapine was associated with the development of cataracts in dogs during the clinical studies and there have also been case reports of humans getting cataracts. My own ... Read More
Hello, everybody, who is interested to be healthy. My name is Kelly. I learnt about depression by my own experience. Now I am ok. Here I want to share my thoughts and ideas how to treat depression symptoms.