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Table of Contents
Static Pages
- About
September 24, 2009, 11:32
On my blog I want to share my thoughts and ideas how to treat depression symptoms.
- Facts on Depression
May 18, 2010, 05:16
Depression is a condition characterised by long-lasting feelings of sadness and hopelessness. People affected by depression usually suffer from the negative…
- Drugs
May 10, 2011, 09:25
Amphetamines (includes some phenylethylamine derivatives) Use: antidepressant; stimulant; antihyperactivity Generic Drug…
- Site Map
August 26, 2010, 08:05
This page contains the site table of contents. Use it to quickly find content on this website.
Blog Posts
- Category: Uncategorized (3)
- SSRIs in anxious depression: Paroxetine by: Kelly
October 7, 2010, 09:57
Paroxetine (Paxil) has produced some of the most striking data showing superior efficacy on anxiety symptoms within depression compared with other antidepressan…
- Treating Dementia With Atypical Antipsychotics. Part 1 by: Kelly
January 4, 2010, 18:03
Patients with dementia display a broad range of cognitive impairments and behavioral and psychotic symptoms. Common behavioral symptoms include verbal and…
- Limbic - Energy Level, Agitation, Emotions by: Kelly
December 26, 2009, 16:37
The noradrenergic projection from the locus coeruleus to limbic cortex may mediate emotions, as well as energy, fatigue, and psychomotor agitation or…
- SSRIs in anxious depression: Paroxetine by: Kelly
- Category: Antidepressants (82)
- Reboxetine Mesilate by: Kelly
December 22, 2010, 05:57
Drug Nomenclature Synonyms: FCE-20124 (reboxetine or reboxetine mesilate); PNU-155950E; Reboxetina, mesilato de; Reboxetine Mesylate BAN: Reboxetine…
- Protriptyline Hydrochloride by: Kelly
December 19, 2010, 05:43
Drug Nomenclature Synonyms: MK-240; Protriptilina, hidrocloruro de BAN: Protriptyline Hydrochloride USAN: Protriptyline Hydrochloride INN: Protriptylin…
- Nortriptyline Hydrochloride by: Kelly
December 16, 2010, 12:26
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and…
- Fluvoxamine Maleate by: Kelly
December 12, 2010, 12:19
Drug Nomenclature Synonyms: DU-23000; Fluvoksamiinimaleaatti; Fluvoxamina, maleato de; Fluvoxamini Maleas; Fluvoxaminmaleat BAN: Fluvoxamine Maleate…
- Trazodone Hydrochloride by: Kelly
December 8, 2010, 11:11
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and…
- Dosulepin Hydrochloride by: Kelly
August 19, 2010, 03:23
Drug Approvals (British Approved Name Modified, rINNM) INNs in main languages (French, Latin, Spanish): Synonyms: Dosulepiinihydrokloridi; Dosulepin-hydro…
- Doxepin Hydrochloride by: Kelly
August 16, 2010, 03:17
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and…
- Duloxetine Hydrochloride by: Kelly
August 13, 2010, 03:13
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and…
- Desipramine Hydrochloride by: Kelly
August 10, 2010, 06:37
Drug Approvals (BANM, US Adopted Name, rINNM) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: DMI;…
- Clomipramine Hydrochloride by: Kelly
August 8, 2010, 06:22
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Chlorimipr…
- Viloxazine Hydrochloride by: Kelly
August 6, 2010, 06:18
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: ICI-58834;…
- Venlafaxine Hydrochloride by: Kelly
August 4, 2010, 06:01
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Venlafaxin…
- Bupropion Hydrochloride by: Kelly
July 17, 2010, 12:42
Drug Approvals (BANM, US Adopted Name, rINNM) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms:…
- Amoxapine by: Kelly
July 17, 2010, 12:31
Drug Approvals (British Approved Name, US Adopted Name, rINN) Synonyms: Amoksapiini; Amoxapin; Amoxapina; Amoxapinum; CL-67772 BAN: Amoxapine USAN:…
- Amitriptyline. Interactions. Uses. Preparations by: Kelly
July 17, 2010, 12:30
Interactions Interactions involving tricyclic antidepressants often result from additive toxicity or from altered metabolism of one drug by the other. Drugs…
- Amitriptyline by: Kelly
July 17, 2010, 11:40
Drug Approvals (British Approved Name, rINN) Synonyms: Amitriptilina; Amitriptyliini; Amitriptylin; Amitriptylinum BAN: Amitriptyline INN: Amitriptyline…
- Recommendations for the Use of Antidepressants by: Kelly
June 30, 2010, 12:19
Allowing for the many limitations, we can generalize from available data to make the following recommendations: 1. All patients with acute major depression…
- Antidepressants: Drug Interactions by: Kelly
June 27, 2010, 08:18
The most common drug interaction with antidepressants is their influence on the metabolism of other drugs. Antidepressants are metabolized through catabolic…
- Antidepressants: Side Effects by: Kelly
June 23, 2010, 08:10
Once the choice of an antidepressant has been made, the main goal is to maximize therapeutic effects and minimize side effects. Good preparation and reassurance…
- Treatment of Partially Responsive and Nonresponsive Patients. 2 by: Kelly
June 20, 2010, 08:07
Continuation and Maintenance Periods, and Discontinuation CONTINUATION PERIOD This period usually lasts five to eight months after the end of the acute…
- Treatment of Partially Responsive and Nonresponsive Patients. 1 by: Kelly
June 19, 2010, 08:05
There is little benefit in making treatment changes before three weeks, other than to mitigate side effects. Changes in treatment strategy should be considered…
- Drug Selection and Initiation of Treatment for Major Depression. Treatment by: Kelly
June 15, 2010, 07:51
Initiation of Treatment Starting doses, titration schemes, and target doses for commonly-used tricyclic antidepressants (TCAs), monoamine oxidase inhibitors…
- Drug Selection and Initiation of Treatment for Major Depression by: Kelly
June 14, 2010, 07:48
On average, all antidepressants are equally effective. Without a personal or family history of response to a particular agent, side effects are the most…
- Indications for Use of Antidepressants by: Kelly
June 10, 2010, 07:34
All antidepressants are indicated for the treatment of acute major depressive episodes; there is also evidence for their use in the prevention and relapse and…
- Antidepressants: Pharmacology by: Kelly
June 5, 2010, 07:29
The use of antidepressants in the treatment of depression remains the best-understood use of these medications; however, there is a growing list of other…
- Amitriptyline by: Kelly
May 24, 2010, 15:49
AMITRIPTYLINE (am-ee-TRIP-till-een) Other Names for this Medication Elavil, Tryptizol, Laroxyl, Sarotex, Apo-amitriptyline, Bio-amitriptyline, Dom-amitriptyli…
- Vestra: Drug for the Treatment of Depression by: Kelly
January 17, 2010, 16:39
Brand Name: Vestra Active Ingredient: reboxetine mesylate Indication: Treatment of depression Company Name: Pharmacia & Upjohn Vestra: Introduction As…
- What is the role of SSRIs in the treatment of social phobia? by: Kelly
December 17, 2009, 10:57
Social phobia has recently been recognized as a chronic and often debilitating disorder. It is estimated to affect up to 10% of the population, with onset…
- Cardiovascular Effects of Antidepressants. Part 3 by: Kelly
November 23, 2009, 07:45
Tricyclic Overdose Cardiovascular Complications. Thorstrand has recently reported clinical variables with special reference to the electrocardiogram in 153…
- Cardiovascular Effects of Antidepressants. Part 2 by: Kelly
November 23, 2009, 07:44
Maprotiline and its Effects on the Cardiovascular System ECG studies in 50 healthy volunteers (ages 18-45) given 50 mg maprotiline tid disclosed minimal…
- Cardiovascular Effects of Antidepressants. Part 1 by: Kelly
November 23, 2009, 07:44
In 1957 Kuhn first described the effectiveness of imipramine in treating depressive states. Since then several derivatives of tricyclic antidepressants (TCA)…
- Antidepressants in Canada by: Kelly
November 23, 2009, 06:33
Since the introduction of tricyclic antidepressants (TCAs) and the monoamine oxidase inhibitors (MAOIs) in the 1950s, the search for more effective antidepressa…
- Antidepressants May Slow Parkinson's disease by: Kelly
November 12, 2009, 04:08
Study hints they block death of nerve cells Discovery of a hitherto unknown mechanism in Parkinson's disease raises the possibility that antidepressants…
- Antidepressants and Elderly by: Kelly
November 12, 2009, 04:02
Risk from SSRIs highest in those over 80, says study The latest generation of antidepressants may have a nasty side effect in older patients, says a new…
- Antidepressants May Cut Heart Attack Risk by: Kelly
November 12, 2009, 03:48
Prozac, Paxil, Zoloft help prevent blood clots A new study supports the theory that one kind of antidepressant drug can help prevent heart disease not only…
- Antidepressants and Depressed Patients by: Kelly
November 10, 2009, 17:22
Preliminary results of a laboratory study, conducted by researchers at the Center for Thrombosis Research at Sinai Hospital in Baltimore and Duke University,…
- Should Mothers on Prozac Breast-Feed? by: Kelly
November 10, 2009, 14:55
Depression drugs, smoking prompt revised guidelines The nation's leading group of baby doctors is revising its advice on when women should not breast-feed.…
- Antidepressants in the Treatment of Dysthymic Disorder. Part 2. Pharmacotherapy by: Kelly
November 9, 2009, 09:10
Pharmacotherapy Clinical trials of dysthymic disorder have been plagued by much variability in duration of treatment, measures of improvement, and patient…
- Antidepressants in the Treatment of Dysthymic Disorder. Part 1 by: Kelly
November 9, 2009, 09:07
This chronic mood disorder is underdiagnosed and inadequately treated, leaving many with an impaired quality of life. Epidemiology and Clinical Features D…
- Antidepressants Are Often Overprescribed for Insomnia by: Kelly
November 9, 2009, 08:44
Treatment of insomnia is largely inadequate, according to sleep researchers. More than 30% of adults in industrialized countries suffer from occasional…
- SSRIs Are Safe in Pregnancy by: Kelly
November 9, 2009, 08:29
Antidepressants do not raise risk of birth defects. Selective Serotonin Reuptake Inhibitors (SSRIs) such as fluvoxamine, paroxetine and sertraline do not…
- SSRIs and Sexual Dysfunction by: Kelly
November 6, 2009, 16:52
Selective serotonin reuptake inhibitors are an effective treatment for depression, but they can be associated with sexual dysfunction, researchers noted to a…
- Selective Serotonin Reuptake Inhibitors in Children by: Kelly
November 5, 2009, 15:55
The safety and effectiveness of most drugs are generally not as well established during clinical trials in children as in adults. Consequently, there is…
- The Use of Antidepressants by: Kelly
October 8, 2009, 09:47
It is well recognized that depressive disorders are very common in general practice. Estimates of the prevalence of depression vary, but a recent estimate puts…
- Principles of Antidepressant Usage by: Kelly
October 4, 2009, 14:39
The introduction of each new antidepressant is accompanied by claims of advantages which are usually expressed in terms of a more rapid onset of action, less…
- SSRI class of antidepressants: pregnant and breastfeeding women by: Kelly
October 3, 2009, 09:09
Treating clinical depression in pregnant and breastfeeding mothers has always required assessing the risk of using a psychotropic medication, which might…
- Newer Antidepressants by: Kelly
October 1, 2009, 22:05
Newer antidepressants are gradually replacing old tricyclic antidepressants because of comparable efficacy with fewer side effects and a much lower risk of…
- Old antidepressants: tricyclic antidepressants by: Kelly
September 29, 2009, 19:56
Depression sufficient to warrant professional care affects 2% to 4% of the general population. Cassem has observed that "92% of all persons suffering from it…
- Category: Celexa (Citalopram) (4)
- Citalopram by: Kelly
July 17, 2010, 13:27
Drug Approvals (British Approved Name, rINN) Synonyms: Citalopram; Citalopramum; Lu-10-171; Sitalopraami BAN: Citalopram INN: Citalopram INN: Citalopram…
- Celexa: SSRI, Popular in Europe, Approved for Depression by: Kelly
November 30, 2009, 04:38
Citalopram (Celexa, Forest Laboratories, Parke-Davis) has been approved by FDA for treatment of depression. A highly selective serotonin reuptake inhibitor,…
- Celexa (Citalopram): Drug-Drug Interactions by: Kelly
September 24, 2009, 19:59
Concomitant administration of imipramine, lithium, and levomepromazine had no effect on Tmax values of citalopram or its metabolites. In contrast, cimetidine…
- Celexa (Citalopram): Proposed Directions for Use by: Kelly
September 24, 2009, 15:32
Directions for use conveyed in the sponsor's proposed labeling are as follows: Citalopram should be administered at a dose of 20 mg once daily. Clinical…
- Citalopram by: Kelly
- Category: Zoloft (Sertraline) (8)
- Sertraline Hydrochlonde by: Kelly
December 25, 2010, 06:05
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and…
- Drug sertraline (Zoloft) therapy for controlling symptoms of premenstrual syndrome by: Kelly
January 19, 2010, 03:59
A new study suggests that the antidepressant drug sertraline (Zoloft), from Pfizer Inc., may be effective in controlling symptoms of premenstrual syndrome…
- The antidepressant drug sertraline (Zoloft) may be effective in panic disorder by: Kelly
January 18, 2010, 16:49
A recent study concludes that the antidepressant drug Zoloft (Sertraline) appears to be effective in reducing the number of panic attacks in patients with…
- Zoloft for Post-Traumatic Stress Disorder by: Kelly
November 12, 2009, 18:39
Zoloft Brand Name: Zoloft Active Ingredient: sertraline hydrochloride Indication: Treatment of posttraumatic stress disorder; also…
- Zoloft Eases Trauma's Aftermath by: Kelly
November 12, 2009, 04:27
Helps 3 in 5 people even without psychotherapy The antidepressant drug sertraline can provide relief from the disabling emotions that follow a traumatic…
- Zoloft Helps premenstrual syndrome (PMS) by: Kelly
November 9, 2009, 08:34
Antidepressant relieves severe menstrual symptoms. Women suffering from a severe form of premenstrual syndrome were helped by Zoloft, according to a study of…
- Zoloft and premenstrual dysphoric disorder by: Kelly
October 4, 2009, 18:38
Research question Is sertraline (Zoloft) effective at improving the symptoms and reducing the functional impairment associated with premenstrual dysphoric…
- Zoloft (Setraline): Review of Systems by: Kelly
September 26, 2009, 13:51
Cardiovascular In the current Zoloft labeling, it is noted that analysis of ECG data from 774 patients receiving sertraline in clinical trials revealed no…
- Sertraline Hydrochlonde by: Kelly
- Category: Prozac (Fluoxetine) (7)
- Fluoxetine Hydrochlonde. Uses. Preparations by: Kelly
August 27, 2010, 04:09
Uses and Administration Prevention of the reuptake of monoamine transmitters such as serotonin, which potentiates their action in the brain, appears to be…
- Fluoxetine Hydrochlonde. Precautions. Interactions by: Kelly
August 26, 2010, 04:07
Precautions Because of their epileptogenic effect SSRIs should be used with caution in patients with epilepsy or a history of such disorders (and should be…
- Fluoxetine Hydrochlonde. Adverse Effects by: Kelly
August 25, 2010, 04:05
Drug Approvals (BANM, US Adopted Name, rINNM) International Nonproprietary Names (INNs) in main languages (French, Latin, Spanish): Synonyms: Fluoksetiinih…
- Antidepressant drug Prozac therapy for bulimia nervosa by: Kelly
January 16, 2010, 16:16
A recent report suggests that the antidepressant drug Prozac (fluoxetine) can be useful in the treatment of bulimia nervosa. * Researchers at the New York…
- SSRI (Prozac - fluoxetine) Use and Suicidal Behavior by: Kelly
December 15, 2009, 09:55
There has been continuing speculation about a relationship between fluoxetine (Prozac) use and increased suicidal behavior since six cases were reported in…
- Drugs and 'Talk Therapy' Compared in Teen Depression by: Kelly
November 9, 2009, 12:28
Study shows decrease in suicidal thoughts from combined therapy. A study funded by the National Institute of Mental Health (NIMH) concludes that Prozac is…
- Prozac Lessens Premenstrual Dysphoric Disorder Symptoms by: Kelly
November 9, 2009, 08:53
Drug lessens severity of premenstrual dysphoria. Intermittent dosages of fluoxetine (Prozac/Lilly) given during the luteal phase of the menstrual cycle may…
- Fluoxetine Hydrochlonde. Uses. Preparations by: Kelly
- Category: Paxil (Paroxetine) (5)
- Paroxetine by: Kelly
December 9, 2010, 13:22
Drug Approvals (British Approved Name, US Adopted Name, rINN) INNs in other languages (French, Latin, and Spanish): Synonyms: BRL-29060; FG-7051;…
- Paxil (Paroxetine) for the treatment of social anxiety disorder & social phobia by: Kelly
January 25, 2010, 11:24
A recent study adds to the body of evidence suggesting that the drug Paxil (paroxetine HCl) is effective in treating social anxiety disorder / social phobia. …
- Paxil to Treat Post Traumatic Stress by: Kelly
November 12, 2009, 04:20
Anti-depressant Paxil joins the list The anti-anxiety drug Paxil (paroxetine HCl) has joined Zoloft as an FDA-approved treatment for post traumatic stress…
- Low Traces of SSRI in Infants by: Kelly
November 9, 2009, 08:31
Study sees treatment option for women who breast-feed. Breast-fed infants of mothers taking the selective serotonin reuptake inhibitor (SSRI) antidepressant…
- Paroxetine (Paxil) for Depression by: Kelly
November 5, 2009, 16:13
The Food and Drug Administration has approved the marketing of the selective serotonin reuptake inhibitor paroxetine hydrochloride (Paxil / SmithKline Beecham)…
- Paroxetine by: Kelly
- Category: Remeron (Mirtazapine) (2)
- Where Does Remeron Fit in Current Antidepressant Therapy? by: Kelly
November 12, 2009, 04:44
Mirtazapine (Remeron / Organon) was approved by the U.S. Food and Drug Administration in 1996 for the treatment of depression. Structurally unrelated to any…
- Mirtazapine (Remeron) for Depression by: Kelly
November 5, 2009, 16:08
The first of a new class of antidepressants - the alpha2-receptor antagonists - has received FDA approval for the treatment of depression. Mirtazapine…
- Where Does Remeron Fit in Current Antidepressant Therapy? by: Kelly
- Category: Seroquel (Quetiapine) (3)
- How To Take Seroquel (Quetiapine Fumarate) by: Kelly
November 28, 2009, 10:41
Please keep the following information in mind when taking Seroquel®(Quetiapine Fumarate). Making Seroquel tablets work for you Seroquel is available…
- The Effect of Seroquel in Long-Term Treatment of Patients With Schizophrenia by: Kelly
November 28, 2009, 09:35
Clinical data recently presented at a major US psychiatric conference suggest that Seroquel ® (Quetiapine Fumarate) Tablets continue to be safe,…
- Facts About Seroquel (Quetiapine Fumarate) Tablets by: Kelly
November 28, 2009, 08:32
• In September 1997, Seroquel was cleared for marketing by the US Food and Drug Administration (FDA). Seroquel is an oral medication indicated for the…
- How To Take Seroquel (Quetiapine Fumarate) by: Kelly
- Category: Zyprexa (olanzapine) (2)
- Zyprexa Approved for Treating Manic Depression by: Kelly
April 11, 2010, 01:10
Brand Name Drug: Zyprexa Active Ingredient Drug: olanzapine Indication: Treatment of manic depression/bipolar disorder Company Name: Eli Lilly and Company I…
- Zyprexa for Manic Depression by: Kelly
April 9, 2010, 01:10
Zyprexa Brand Name: Zyprexa Active Ingredient: olanzapine Indication: Treatment of manic depression (bipolar disorder); also…
- Zyprexa Approved for Treating Manic Depression by: Kelly
- Category: Lexapro (Escitalopram Oxalate) (3)
- Escitalopram Oxalate by: Kelly
August 22, 2010, 03:26
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: S-Citalopr…
- Currently Taking Lexapro by: Kelly
May 18, 2010, 06:52
If you've already been prescribed LEXAPRO, you've taken the all-important first step toward improving your depression. Now you may be wondering what to…
- Lexapro: the Process of Treatment by: Kelly
May 14, 2010, 06:41
Fortunately, it's very easy to seek treatment for depression today. And in most cases, treatment with medications like LEXAPRO can effectively restore quality…
- Escitalopram Oxalate by: Kelly
- Reboxetine Mesilate by: Kelly
- Category: Depression (71)
- The Murder of the Self: Men and Suicide by: Kelly
August 8, 2011, 09:57
Religious and bureaucratic prejudices, family sensitivity, the vagaries and differences in the proceedings of corner's courts and post-mortem examinations, the…
- Suicide In Men: The Facts by: Kelly
August 8, 2011, 09:55
When data on suicide are examined closely, the grim reality of the impact of depression on men is obvious. Studies of suicide have consistently found that men…
- Comorbidity And Suicide In Men by: Kelly
August 8, 2011, 09:54
Men and women who make suicide attempts and who commit suicide have been found to suffer from a number of psychiatric and psychological disturbances. In…
- Increased Risk Of Suicide In Men by: Kelly
August 8, 2011, 09:52
Data on suicide attempts and completions clearly paint a grim picture for depressed men: depressed men complete suicide in very high numbers. Even if it is…
- Assessment Of Suicide Risk In Men by: Kelly
August 8, 2011, 09:51
In light of men's higher risk for suicide, careful assessment of suicide risk is essential when treating men for depression. This assessment of risk in men…
- Management Of Suicide Risk by: Kelly
August 8, 2011, 09:50
Assessment of suicide risk invariably directs clinician attention to the management of suicide risk. Goals and strategies for management of suicide risk may…
- Psychopharrnacologic Treatment of Depression in Men by: Kelly
August 8, 2011, 09:46
I could feel the tears within me, undiscovered and untouched in their inland sea. Those tears had been with me always. I thought that, at birth, American…
- Antidepressants And Depression In Men by: Kelly
August 8, 2011, 09:45
Though the population-based data demonstrate equal response to antidepressant medication, there are, of course, compelling reasons to choose a particular…
- Testosterone And Depression In Men by: Kelly
August 8, 2011, 09:43
Another issue which is unique to the assessment and treatment of depressed men is the potential role played by testosterone in the genesis and maintenance of…
- Assessing Depression in Men by: Kelly
August 8, 2011, 09:19
He who conceals his disease cannot expect to be cured. Ethiopian Proverb The title of Whybrow's (1997) popular treatise on mood disorders, "A Mood Apart,"…
- Symptom Profiles In Mood Disorders by: Kelly
August 8, 2011, 09:18
A primary consideration in the assessment of depression is a careful review of the individual's symptoms. A diagnosis of depression, as defined in the fourth…
- Instruments To Assess Depression by: Kelly
August 8, 2011, 09:16
In addition to structured clinical interview methods for assisting the clinician in assessing depression, there are a number of popular self-report measures…
- Masculine-Specific Assessment Of Depression by: Kelly
August 8, 2011, 09:14
Pollack (1998a) has proposed a change in the way clinicians assess male depression. This new approach to assessing depression in men emphasizes the important…
- Loss, Trauma, Grief and Masked Depression in Men by: Kelly
August 8, 2011, 09:11
Much obviously remains to be learned (and a great deal will doubtless continue to be a mystery, owing to the disease's idiopathic nature, its constant…
- Normative Loss Across The Life Span by: Kelly
August 8, 2011, 09:09
A number of psychoanalytically informed theorists,have pointed out the gender-bifurcated impact of our culture's child-rearing practices. In these conceptualiza…
- Trauma And Depression by: Kelly
August 8, 2011, 09:07
Trauma involves a severe disturbance of an individual's mental and emotional life through a painfully inflicted experience or series of experiences from…
- Grief and Depression by: Kelly
August 8, 2011, 09:05
Grief is defined as the physical and emotional state and the behaviors that accompany the permanent loss of a significant other. Much of the research literature…
- Manifestations Of Covert Depression In Men by: Kelly
August 8, 2011, 09:04
Biopsychosocial models of depression emphasize a complex interplay of biological and genetic vulnerability, psychological mechanisms, and behavioral tendencies…
- Marital Functioning and Depression by: Kelly
May 26, 2011, 10:32
Researchers have focused specifically on the quality of the marital and romantic relationships of depressed individuals to better understand the role of…
- Maltreatment and Depression by: Kelly
May 26, 2011, 10:15
Childhood maltreatment, including physical abuse, emotional maltreatment, sexual abuse, and neglect, has long been implicated in the development of depression…
- Loss by: Kelly
May 26, 2011, 10:13
The notion that painful life experience is critically linked with depressive illness is in no way new. On the one hand within orthodox psychiatry, well before…
- Intrusive Memory by: Kelly
May 25, 2011, 09:58
Many patients with depression, like those with posttraumatic stress disorder (PTSD), experience unwanted memories of one or more significant events in their…
- Interpersonal Model of Depression by: Kelly
May 25, 2011, 09:46
The interpersonal approach to depression focus on interactional patterns as a primary source of the onset and maintenance of depression. The interpersonal…
- Internalizing Disorders by: Kelly
May 25, 2011, 09:43
Reynolds (1992) described internalizing disorders in children and adolescents as "a class of disorders that are considered to be inner-directed, in which core…
- Internal Working Models by: Kelly
May 25, 2011, 09:40
The idea of an internal working model was proposed by Bowlby (1980). Internal working models are seen as so-called cognitive-interpersonal blueprints that form…
- Expressed Emotion by: Kelly
May 24, 2011, 12:12
Expressed emotion (EE) is a relational construct that provides a measure of the family environment. Its origins come from schizophrenia research. However,…
- Depressogenesis by: Kelly
May 24, 2011, 11:56
Two terms that are used frequently in the cognitive depression literature, but that apply to all theoretical domains, are depressotypic and depressogenic.…
- Melancholia by: Kelly
May 24, 2011, 11:49
The term melancholia has origins in the humoral theory, which imputed disease as reflecting an imbalance in one or more of the bodily humors — blood, black…
- Managing Resistant Depression. Part 8 by: Kelly
May 2, 2011, 10:36
Absolute treatment resistance In most surveys, the number of patients with absolute treatment resistance is very small. In some specialized tertiary…
- Impact of Depression on Earnings by: Kelly
March 31, 2010, 08:07
The raging controversy in managed care continues to focus on whether reducing expenditures actually means saving money. Recent data published in The American…
- Depression In The Elderly: Treatment Of Depression by: Kelly
December 22, 2009, 15:29
Treatment of depressive disorders may involve psychopharmacology, psychotherapy, or both. Studies have shown that for mild depression, psychotherapy was more…
- Depression In The Elderly: Outcome Of Depressive Disorder. Suicide by: Kelly
December 21, 2009, 15:28
Depressive disorder untreated can last 7 to 14 months and longer than 2 years. In the elderly, a pathological grieving process that has progressed to an…
- Depression In The Elderly: Presentation Of Depression In The Elderly by: Kelly
December 20, 2009, 15:27
The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) enumerates a total of nine criteria for the diagnosis of major…
- Depression In The Elderly: Epidemiologic Studies Of Depression by: Kelly
December 19, 2009, 15:19
Major depressive disorder occurs throughout the life cycle. Longitudinal data suggest a changing pattern in the age of onset in the United States. In more…
- Depression and Psychosis: Improving Outcomes by: Kelly
December 14, 2009, 08:30
The following is the question and answer session from the Depression and Psychosis: Improving Outcomes. The presenters were Richard G. Petty, M.D., and Jack M.…
- Tranquillizer and Antidepressant Drugs in Practice. Part 3 by: Kelly
November 27, 2009, 08:04
(Country: Canada) Psychiatric Problems in Children Tranquillizers have been used to a moderate degree in the treatment of similar psychiatric conditions in…
- Tranquillizer and Antidepressant Drugs in Practice. Part 2 by: Kelly
November 27, 2009, 08:03
(Country: Canada) Miscellaneous Group The drugs in the miscellaneous group which are most widely used are meprobamate and Librium. Meprobamate is marketed…
- Tranquillizer and Antidepressant Drugs in Practice. Part 1 by: Kelly
November 27, 2009, 08:01
(Country: Canada) A healthy controversy continues to be manifested in the field of psychiatry concerning the use of drug therapy. This controversy is related…
- Depression and Cocaine Use by: Kelly
November 27, 2009, 04:23
In clinical practices and research program we have commonly observed dual diagnoses in patients with serious disorders of alcohol or other substance abuse. One…
- Early detection of depression. Part 4 by: Kelly
November 26, 2009, 07:48
Special problems The early detection of depression is much more complex and challenging than the detection of other conditions seen in the primary care…
- Early detection of depression. Part 3 by: Kelly
November 26, 2009, 07:47
Effectiveness of early detection The critical question with any intervention for early detection and treatment is whether it does more good than harm as…
- Early detection of depression. Part 2 by: Kelly
November 26, 2009, 07:46
Are there acceptable routine screening tests? Instruments for routine case-finding in primary care settings must be of acceptable quality, brief and easy…
- Early detection of depression. Part 1 by: Kelly
November 26, 2009, 07:28
Depression is common and can usually be treated effectively. However, in many cases physicians may not recognize depression, especially in its early stages.…
- Adolescent depression. Treatment. Part 4 by: Kelly
November 25, 2009, 08:06
Pharmacotherapy Antidepressant medication has been surprisingly inefficacious for adolescents. In contrast to open studies, placebo-controlled, double-blin…
- Adolescent depression. Treatment. Part 3 by: Kelly
November 25, 2009, 08:05
Cognitive therapy strategies. During several 20-minute sessions scheduled about every 2 weeks, cognitive behavioural therapy can be introduced to teens in a…
- Adolescent depression. Treatment. Part 2 by: Kelly
November 25, 2009, 08:04
Psychotherapy Table 1 outlines psychotherapeutic approaches to adolescent depression. The emphasis is on cognitive therapy and behavioural strategies that…
- Adolescent depression. Treatment. Part 1 by: Kelly
November 25, 2009, 07:59
Résumé (French Language) Le traitement de la dépression chez les adolescents comporte de multiples modalités, incluant des interventions de nature…
- Adolescent depression. Diagnosis. Part 4 by: Kelly
November 24, 2009, 03:57
Comorbidity Comorbidity is the simultaneous occurrence of more than one diagnosis. Comorbidity complicates research on the etiology and outcome of a single…
- Adolescent depression. Diagnosis. Part 3 by: Kelly
November 24, 2009, 03:56
Differential diagnosis If unhappiness is common, how do we know an adolescent is clinically depressed rather than having "normal" teenage…
- Adolescent depression. Diagnosis. Part 2 by: Kelly
November 24, 2009, 03:55
Risk factors An awareness of risk factors can help a physician detect the potential for clinical depression in a particular young person. Risk factors for…
- Adolescent depression. Diagnosis. Part 1 by: Kelly
November 24, 2009, 03:52
Résumé (French Language) Chez les adolescents, la dépression clinique amène une morbidité significative, incluant une détresse somatique et une…
- Managing Resistant Depression. Part 7 by: Kelly
November 22, 2009, 04:56
Other augmentation strategies. In addition to lithium, other agents have been described as augmentors, depending on the antidepressant used. Triiodothyron…
- Managing Resistant Depression. Part 6 by: Kelly
November 22, 2009, 04:54
Specific approaches to treatment-resistant depression A stepped-care approach should be used to manage depression. Figure 1 summarizes the various steps and…
- Managing Resistant Depression. Part 5 by: Kelly
November 22, 2009, 04:50
Assessment of current treatment. The most frequent reason that a patient does not respond to treatment and becomes labeled as treatment resistant is the…
- Managing Resistant Depression. Part 4 by: Kelly
November 22, 2009, 04:49
Underlying physical factors. Many physical diseases present with depressive symptoms or complicate a depressive illness. Many of these illnesses remain…
- Managing Resistant Depression. Part 3 by: Kelly
November 22, 2009, 04:47
Factors involved in treatment failure Several questions must be asked when assessing a patient who has failed to respond to treatment. Is the diagnosis of…
- Managing Resistant Depression. Part 2 by: Kelly
November 22, 2009, 04:43
Definition Treatment-resistant depression is difficult to define. The term embraces many variables that can influence response to treatment. Treatment-resistan…
- Managing Resistant Depression. Part 1 by: Kelly
November 22, 2009, 04:42
The World Health Organization identified mood disorders as a significant public health problem more than a decade ago. Some evidence suggests that the…
- SSRIs and Sexual Dysfunction by: Kelly
November 22, 2009, 02:59
Selective serotonin reuptake inhibitors are an effective treatment for depression, but they can be associated with sexual dysfunction. To improve compliance…
- Panic Symptoms Predict Poor Response to Depression Treatment by: Kelly
November 20, 2009, 02:26
Evidence indicates that patients with major depression and co-occurring anxiety features are at risk for more severe symptoms and less favorable outcome than…
- Childhood Depression by: Kelly
November 19, 2009, 02:11
It is estimated that 1.9% of primary school children and 4.7% of adolescents are affected by depression; the consequences of depression in this age group can…
- Defeating Depression! by: Kelly
November 12, 2009, 03:51
Therapy, medication can give you back your life If you're suffering from clinical depression, you might be reluctant to tell anyone how you feel. Unfortunate…
- Vitamin B12 Deficiency Linked to Depression in Older Women by: Kelly
November 11, 2009, 17:08
Brenda Penninx, Ph.D., and colleagues from The Johns Hopkins University, the University of Colorado in Denver and Vrije University in the Netherlands have…
- Seniors Downplay Clinical Depression by: Kelly
November 9, 2009, 08:50
Attitudes of Older Americans Toward Depression Percent of Americans 65 years or older Know Little 68% View as Health Problem 38…
- Depression in the Elderly by: Kelly
November 9, 2009, 08:42
Depression in late life is a treatable disorder and is not a part of the normal aging process, points out Ira R. Katz, M.D., a professor of psychiatry at the…
- Unemployment Payments Protect Against Depression by: Kelly
November 7, 2009, 16:45
Unemployment payments not only provide an economic buffer for unemployed women but also are effective protection against depression. But welfare is not…
- Three of Four Depression Categories Are Mostly Homogeneous by: Kelly
November 2, 2009, 17:01
In order to examine the validity of diagnostic categories of depression, Li-Shiun Chen, M.D., and colleagues from The Johns Hopkins University charted the…
- Resistant depression by: Kelly
October 16, 2009, 04:48
More than 20% of patients with major depression have not recovered after 2 years and, of those who do initially recover, 20% suffer a relapse 1 year later.…
- Anxiety and Depression by: Kelly
October 12, 2009, 09:49
Anxiety and depression are common symptoms of a failure to cope with mental stress. Traditional treatments for these conditions have often involved psychotherap…
- The Classification of Depression by: Kelly
September 25, 2009, 01:10
Current concepts of classification The classification of depression is a broad topic, sufficient to keep armies of psychiatrists disputing happily for…
- Understanding Depression by: Kelly
September 24, 2009, 00:11
There are three levels of symptoms to watch for: somatic symptoms, strategies to relieve discomfort, and social withdrawal. Somatic Symptoms The primary…
- The Murder of the Self: Men and Suicide by: Kelly
- Category: Book review (32)
- Cultural Issues in the Treatment of Anxiety by: Kelly
May 3, 2011, 10:52
Friedman S, editor New York, London: The Guilford Press; 1997. 261 pp. with index ISBN 1-57230-237-2 Anxiety is a profound human experience. Anxiety…
- The Treatment of Anxiety Disorders by: Kelly
March 16, 2010, 14:51
The Treatment of Anxiety Disorders: Clinician's Guide and Patient Treatment Manuals Gavin Andrews, Rocco Crino, Caroline Hunt, Lisa Lampe, Andrew Page, 423…
- Drug Use In Assisted Suicide And Euthanasia by: Kelly
March 13, 2010, 01:20
Editors: Margaret P. Battin, Arthur G. Lipman Pharmaceutical Products Press, 10 Alice St, Binghamton, NY 13904-1580 USA 1996/360 pp Balanced…
- Antidepressants - thirty years on by: Kelly
February 1, 2010, 19:49
Brian Leonard and Paul Spenser, eds. Colchester: Portland Press, 1991, 516 pp ISBN 1-869868-74-9 The Royal College of Psychiatrists and the Royal…
- Treating mental illness in primary care by: Kelly
January 23, 2010, 06:33
Managing Mental Health Problems. A Practical Guide for Primary Care Nick Kates, Marilyn Craven Hogrefe & Huber Publishers, 12 Bruce Park Ave,…
- Psychiatric Primary Care by: Kelly
January 22, 2010, 06:33
Linda Denise Oakley, Claudette Potter Mosby-Year Book, Inc, 11830 Westline Industrial Dr, St Louis, MO 63146 USA 1997/448 pp Strengths Assessment…
- Recognizing depression in adolescents by: Kelly
January 21, 2010, 21:07
Helping Your Depressed Teenager. A Guide for Parents and Caregivers Gerald D. Oster, Sarah S. Montgomery John Wiley & Sons Canada, Ltd, 5353…
- Practical management in psychiatry by: Kelly
January 20, 2010, 05:13
Psychological Problems in General Practice A.C. Markus; C. Murray Parkes; P. Tomson; M.Johnston Oxford University Press, 70 Wynford Dr, Don Mills, ON M3C…
- Research Methods in Psychiatry by: Kelly
December 31, 2009, 20:57
Research Methods in Psychiatry: A beginner's guide Chris Freeman and Peter tyrer (eds) The Royal College of Psychiatrists, London 1989, 240 pages No…
- Anxiety and Stress Management by: Kelly
December 31, 2009, 19:55
Trevor J Powell and Simon J Enright Routledge, Chapman and Hall, London 1989, 196 pages This useful book is the first in a series on strategies for…
- Managing Anxiety: A Training Manual by: Kelly
December 22, 2009, 20:53
Helen Kennerley Oxford University Press 1990, 177 pages Anxious patients can be treated in many ways and as general practitioners we have numerous…
- Measuring Stress by: Kelly
December 1, 2009, 23:01
Cohen S, Kessler RC, Underwood Gordon L, editors New York: Oxford University Press; 1997. 236 pp. with index ISBN 0-19-512120-1 (paper) "Stress"…
- Depression And The Social Environment by: Kelly
November 29, 2009, 15:53
Depression And The Social Environment: Research And Intervention With Neglected Populations Editors: Philippe CappeUez; Robert J. Flyrm McGill Queen's…
- Risk Management with Suicidal Patients by: Kelly
November 28, 2009, 13:20
Risk Management with Suicidal Patients Bongar B, Berman AL, Mavis RW, Silverman MM, Harris EA, Pakman WL, editors New York: The Guilford Press;…
- Drug Therapy: Decision Making Guide by: Kelly
November 21, 2009, 11:03
Edited by James McCormack, Glen Brown, Marc Levine, Robert Rangno and John Ruedy. 550 pp. W.B. Saunders Company/Harcourt Brace & Company, Philadelphia;…
- Mental Health Law and Practice by: Kelly
November 20, 2009, 11:01
Julio Arboleda-Florez and Margaret Copithorne. Illust Carswell, Scarborough, Ont. 1995 ISBN 9547062-855 This looseleaf book, subtitled "a Guide to the…
- The Anxiety and Phobia Workbook by: Kelly
November 19, 2009, 10:59
The Anxiety and Phobia Workbook, 2nd ed. Edmund J. Bourne. 428 pp. New Harbinger Publications, Inc. 1995 ISBN 1-57224-003-2, paperback; ISBN 1-57224-004-0…
- Physiotherapy in Mental Health by: Kelly
November 18, 2009, 10:57
Physiotherapy in Mental Health: a Practical Approach Edited by Tina Everett, Maureen Dennis and Eirian Rick-etts. 424 pp Must. Butterworth-Heinemann,…
- Psychotherapy for schizophrenia by: Kelly
November 17, 2009, 10:41
The Dinosaur Man: Tales of Madness and Enchantment from the Back Ward Susan Baur. 203 pp Edward Burlingame Books, Harper Collins Publishers, New York.…
- Suicide: Right or Wrong? by: Kelly
November 16, 2009, 10:40
Edited by John Donnelly Contemporary Issues in Philosophy; series editors, Robert M. Baird and Stuart E. Rosenbaum. 212 pp Prometheus Books, Buffalo, NY.…
- Living and Working with Schizophrenia
by: Kelly
November 15, 2009, 10:39
Living and Working with Schizophrenia, 2nd ed. J.J. Jeffries, E. Plummer, M.V. Seeman and J.F. Thornton. 148 pp. University of Toronto Press, Toronto.…
- The Encyclopedia of Phobias, Fears, and Anxieties by: Kelly
November 14, 2009, 10:37
Ronald M. Doctor and Ada P. Kahn. 487 pp. Illust Facts on File, New York, 1989 ISBN 0-8160-1798-0 Have you ever wondered what aichurophobia is and been…
- Handbook of Essential Psychopharmacology by: Kelly
November 13, 2009, 06:33
Handbook of Essential Psychopharmacology Pies RW Washington: American Psychiatric Press; 1998. 416 pp. with index ISBN 0-88048-765-8 This concise,…
- Cognitive Vulnerability to Depression by: Kelly
November 7, 2009, 08:08
Ingram RE, Miranda J, Segal ZV New York: The Guilford Press; 1998. 330 pp with index ISBN 1-57230-304-2 (cloth) What does it mean to be vulnerable…
- Drug Action in the Central Nervous System by: Kelly
November 7, 2009, 07:33
Carvey PM Oxford (UK): Oxford University Press; 1997 ISBN 0-19509-334-8 Understanding the pharmacodynamics, or actions, of drugs is essential in central…
- Psychotropic Drug Handbook by: Kelly
November 7, 2009, 07:31
Psychotropic Drug Handbook, 7th Edition Perry PJ, Alexander B, Liskow BI Washington (DC): American Psychiatric Press; 1997. 740 pp with index ISBN…
- Dysthymia and the Spectrum of Chronic Depressions by: Kelly
November 7, 2009, 07:23
Akiskal HS, Cassano GB (editors) New York: The Guilford Press; 1997. 228 pp with index ISBN 1-57230-089-2 (cloth) This is a very good book about a…
- The Encyclopedia of Depression by: Kelly
October 22, 2009, 07:29
The Encyclopedia of Depression. Roberta Roesch. 263 pp. Facts on File, New York. 1991. ISBN 0-8160-1936-3 Those who work in mental health areas…
- Ask the Doctor: Depression by: Kelly
October 10, 2009, 09:49
Ask the Doctor: Depression Vincent Friedewald Andrews McMeel Publishing, Kansas City. 1998. 114 pp. Illust. ISBN 0-8362-2711-5 Overall rating: Very…
- Handbook of Depression by: Kelly
October 6, 2009, 04:43
Handbook of Depression. Second Edition EE Beckham, WR Leber, editors New York: Guilford Press; 1995. 628 p This multiauthor book is edited by E Edward…
- Review book: Natural Prozac by: Kelly
September 30, 2009, 22:05
Natural Prozac: Learning to Release Your Body's Own Anti-Depressants. Joel C. Robertson and Tom Monte. 215 pp. HarperCollins Publishers, Inc., New…
- Review book: Speaking of sadness by: Kelly
September 28, 2009, 15:21
Speaking of sadness. Depression, disconnection, and the meanings of illness David A. Karp Oxford University Press Canada, 1996, 240 pp Strengths…
- Cultural Issues in the Treatment of Anxiety by: Kelly
- Category: Pharmacotherapy (9)
- Case: Antidepressant agents. Questions - Answers by: Kelly
June 3, 2010, 09:26
Questions Which of the following agents is contraindicated in a patient with epilepsy? A. Bupropion B. Fluoxetine C. Mirtazapine D. Venlafaxine …
- Case: Antidepressant agents. Discussion by: Kelly
June 2, 2010, 09:17
Class Drugs used to treat depression are classified as TCAs, atypical heterocyclic (second- and third-generation) agents, SSRIs, and monoamine oxidase…
- Case: Antidepressant agents by: Kelly
June 1, 2010, 09:17
A 30-year-old woman presents to your office for the evaluation of fatigue. For the past 2 months she has felt run down. She says that she doesn't feel like…
- Treatment-Resistant Schizophrenia May Respond to High-Dose Atypical by: Kelly
April 6, 2010, 05:03
Results from a recent study suggest that olanzapine (Zyprexa) given in moderate to high doses may be useful in treating schizophrenia in patients who have…
- Treating Dementia With Atypical Antipsychotics. Part 2 by: Kelly
January 5, 2010, 09:05
Atypical Antipsychotics Most initial published data on atypical antipsychotic drugs in the elderly are clinical trials in nondemented patients with schizophren…
- Treating Dementia With Atypical Antipsychotics. Part 1 by: Kelly
January 4, 2010, 18:03
Patients with dementia display a broad range of cognitive impairments and behavioral and psychotic symptoms. Common behavioral symptoms include verbal and…
- Pharmacological treatment of depression by: Kelly
October 5, 2009, 14:54
Major depression affects 5% to 10% of patients seen by primary care physicians. Despite the advent of new antidepressant drugs, up to 20% of patients remain…
- Panic Disorder by: Kelly
October 2, 2009, 01:35
Though panic disorder and panic disorder with agoraphobia or phobic avoidance (PDA) are common (the mean lifetime prevalence of panic disorder is 1.5%), the…
- The Pharmacotherapy of Depression by: Kelly
September 27, 2009, 09:28
Over the years, most of the research into the pharmacotherapy of major depression has focused on the treatment of the acute depressive episode. There is a…
- Case: Antidepressant agents. Questions - Answers by: Kelly
- Category: Psychiatry (1)
- Abbreviation by: Kelly
September 24, 2009, 00:00
AE - Adverse Event CRF - Case Report Form DCT - Demethylcitalopram DDCT - Didemethyl Metabolite DSU - Drug Surveillance Unit ECG - Electrocardiogram ISS…
- Abbreviation by: Kelly
- Category: Pharmacology (6)
- Amphetamines by: Kelly
May 10, 2011, 09:49
History's first true antidepressants were the amphetamines. As stimulants, they appear to have an elective effect on low mood (but make anxiety worse). So they…
- Barbiturates by: Kelly
May 10, 2011, 09:47
In the late nineteenth century, a slew of new treatments started to become available thanks mainly to the magic of the German chemical industry. In 1857, the…
- The Earliest Effective Drugs by: Kelly
May 10, 2011, 09:46
In terms of medication, there have always been drugs to soothe the mind and tame the agitated spirit. Alkaloids, widely found in nature, especially in plants…
- Some Griefs Are Medicinable by: Kelly
May 10, 2011, 09:44
What does a world without psychopharmacology look like? In 1913, Mr. X, a 25-year-old employee of the London branch of a Swiss bank, came to see Dr.…
- How are 5-HT2 selective antagonists different from current drug therapy in schizophrenia? by: Kelly
December 11, 2009, 10:14
There a two major classes of agents currently used to treat schizophrenia - the older neuroleptics (typical antipsychotics) and the newer atypical antipsychotic…
- What is the role of serotonin in psychotic disorders? by: Kelly
December 10, 2009, 10:01
The precise role of serotonin (5-HT) in psychotic disorders is not fully understood. However, a variety of preclinical and clinical data suggest that 5-HT is…
- Amphetamines by: Kelly
- Category: Drugs (17)
- Lithium by: Kelly
May 10, 2011, 09:58
By rights, lithium should come first in a discussion of the first drug set, because its effectiveness was discovered — or more properly rediscovered — in…
- Tricyclic Antidepressants by: Kelly
May 10, 2011, 09:57
The success of chlorpromazine wonderfully concentrated minds in the pharmaceutical industry. The discovery did seem capable of being reproduced. Chlorpromazine'…
- Energizers by: Kelly
May 10, 2011, 09:57
In 1957 Hoffmann-La Roche secured from the FDA a depression indication for iproniazid, their drug brand-named Marsilid, that had been on the market for…
- Chlorpromazine and the Phenothiazines by: Kelly
May 10, 2011, 09:55
Yet the concept of tranquilizer was validated in the usefulness of chlorpromazine and other phenothiazine antipsychotics as antidepressants. Antipsychotics as…
- Dissolving the Tranquilizer Unity by: Kelly
May 10, 2011, 09:54
In the late 1950s the tranquilizer spectrum started to be hammered apart with the reification of specific drug categories such as antipsychotics, antidepressa…
- Meprobamate by: Kelly
May 10, 2011, 09:54
As the Ritalin story was unfolding, Frank Berger was searching for a longer-acting mephenesin, the drug with such salutary effects on cerebral palsy at the…
- Methylphenidate by: Kelly
May 10, 2011, 09:53
It is difficult for clinicians of the twenty-first century to accept that they might be offering their patients medications that are less effective than those…
- Reserpine by: Kelly
May 10, 2011, 09:52
Although mephenesin was the first tranquilizer, it wasn't billed as one. Philadelphia psychiatrist Benjamin Rush initially used the term tranquilizer, early…
- Mephenesin by: Kelly
May 10, 2011, 09:52
It is the Second World War. Frank Berger, a Jewish refugee from Nazi Germany who was born in Pilsen, Austro-Hungary, in 1913 and graduated in medicine in…
- Drug interactions: cytochrome P450. Part 8 by: Kelly
November 9, 2009, 08:23
Role of Pharmacist There is no guide, chart, or computer software program for clinicians to clearly identify or quickly predict which drugs interact with…
- Drug interactions: cytochrome P450. Part 7 by: Kelly
November 9, 2009, 08:23
CYP2C Isoenzyme Metabolism The CYP2C subfamily consists of 2C9, 2C10, and 2C19 isozymes as well as others. While these enzymes metabolize a smaller number…
- Drug interactions: cytochrome P450. Part 6 by: Kelly
November 9, 2009, 08:22
CYP1A2 Isoenzyme Metabolism Approximately 15% of all drugs used today are metabolized by the CYP1A2 isozyme. It is generally believed that there is no…
- Drug interactions: cytochrome P450. Part 5 by: Kelly
November 9, 2009, 08:21
CYP2D6 Isoenzyme Metabolism About 25% of all drugs used today are substrates for the CYP2D6 isozyme. This isozyme has been studied extensively. It greatly…
- Drug interactions: cytochrome P450. Part 4 by: Kelly
November 9, 2009, 08:17
CYP3A4 Isoenzyme Metabolism The CYP3A enzyme family is composed of four isozymes involved with metabolism: CYP3A, CYP3A4, CYP3A5, and CYP3A7. Of these, the…
- Drug interactions: cytochrome P450. Part 3 by: Kelly
November 9, 2009, 08:15
Metabolism These CYP enzymes are present in every cell and are responsible for metabolizing or detoxifying consumed foreign (i.e., xeno) biological…
- Drug interactions: cytochrome P450. Part 2 by: Kelly
November 9, 2009, 08:15
Genetic Polymorphism Genetic polymorphism plays a major role modulating drug interactions with the CYP metabolic enzyme system,and contributes to the…
- Drug interactions: cytochrome P450. Part 1 by: Kelly
November 9, 2009, 08:11
This installment focuses on drug interactions as a consequence of metabolism by the cytochrome P450 (CYP) enzyme system. Due to the complexity of this enzyme…
- Lithium by: Kelly
- Category: Disorders (50)
- Anxiety Disorders: Presentation by: Kelly
May 5, 2011, 11:12
Anxiety is a physiological and psychological state of increased arousal that is universal in humans. It can be considered one of the vital factors for the…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 3 by: Kelly
May 4, 2011, 11:02
Causes There are two ways to describe the causes of agitation and aggression: by the underlying disease state (see Table 1), or the exact pathophysiology…
- The Elderly: Insomnia, Depression, and Suicide Risk. Part 3 by: Kelly
December 22, 2010, 05:57
General Principles of Pharmacologic Intervention A thorough history, physical examination, and basic laboratory studies are important to fully evaluate the…
- Anxiety Disorders: Diagnosis and Treatment Approach to Anxiety Disorders by: Kelly
February 24, 2010, 05:11
Diagnosis of uncomplicated anxiety disorders may be made by competent physicians in many specialties who have a thorough understanding of the etiology, signs…
- Anxiety Disorders: Post-traumatic Stress Disorder & Social Phobia by: Kelly
February 21, 2010, 05:07
Post-traumatic Stress Disorder (PTSD) Post-traumatic Stress Disorder (PTSD) has become much more recognized and appreciated following the traumatic events of…
- Anxiety Disorders: Generalized Anxiety Disorder (GAD) by: Kelly
February 18, 2010, 05:03
Once thought to be a rather uncomplicated and mild form of anxiety, generalized anxiety disorder (GAD) has been found to be a much more significant psychiatric…
- Anxiety Disorders: Obsessive Compulsive Disorder (OCD) by: Kelly
February 15, 2010, 14:59
Obsessions are recurrent, distressing thoughts that a person experiences without the ability to control the frequency and intensity of these intrusive…
- Anxiety Disorders: Why Many Patients Do Not Seek Treatment by: Kelly
February 13, 2010, 04:56
Nearly one-half of patients with panic attacks do not seek care for their problem. Patients may endure symptoms for years before they seek treatment. For…
- Anxiety Disorders: Where Patients Seek Treatment by: Kelly
February 11, 2010, 04:54
Where Patients Seek Treatment A large number of patients with an anxiety disorder never seek treatment. These reasons will be discussed in depth in the next…
- Anxiety Disorders: Consequences of Neurotransmitter Mobilization by: Kelly
February 10, 2010, 04:53
Of the adrenergic nervous system's many functions, one, the "fight or flight" response, has served humans well. This response occurs whenever one encounters a…
- Anxiety Disorders: Panic Attack by: Kelly
February 7, 2010, 04:31
A common component of an anxiety disorder is the panic attack. A panic attack may be a familiar experience to many, as 15% of people have reported the…
- Adolescents and Sleep Disorders by: Kelly
January 31, 2010, 13:22
54%–75% of adolescents "wish for more sleep" It is widely recognized that many older Americans suffer from a variety of sleep disorders. In fact, more…
- Major Depressive Disorder by: Kelly
January 30, 2010, 13:15
The American Psychiatric Association (1983) reports that recurrent episodes occur in at least 50% of patients who seek treatment for major depressive disorder…
- No Panic in Panic Attack Treatment by: Kelly
January 29, 2010, 13:04
Success shown with drugs and psychotherapy People plagued by panic attacks need not fear one thing: Treatment works. Panic disorders respond well to…
- Depression and Chronic Pain: Breaking the Cycle by: Kelly
November 13, 2009, 06:25
Chronic Pain. Depression. They are regarded as the one-two punch that — even as we refine and improve medical and pharmaceutical technology — keeps…
- Anxiety Disorders on the Rise by: Kelly
November 10, 2009, 14:05
But treatments are increasingly effective Feeling anxious? You're not alone. According to an article from the Chicago Tribune, published in the The…
- SSRIs and Treatment of Panic Disorder. Part 2 by: Kelly
November 9, 2009, 13:31
Selective Serotonin Reuptake Inhibitors Most recently, the selective serotonin reuptake inhibitors (SSRIs) have provided an alternative to the older…
- SSRIs and Treatment of Panic Disorder. Part 1 by: Kelly
November 9, 2009, 13:30
As many as 70% of patients with panic disorder fulfill the diagnostic criteria for major depression at some point in their lives. Epidemiology and Clinical…
- Sleep Disorders: Insomnia. Part 8 by: Kelly
November 9, 2009, 13:25
Patient Education Tips to Help Patients Improve Sleep Did you know that your behavior can affect how well you sleep? It can be helpful to…
- Sleep Disorders: Insomnia. Part 7 by: Kelly
November 9, 2009, 13:24
Novel Nonbenzodiazepine Hypnotic Drugs Zolpidem: Zolpidem was marketed in the United States in the early 1990s as the first nonbenzodiazepine hypnotic with…
- Sleep Disorders: Insomnia. Part 6 by: Kelly
November 9, 2009, 13:22
Dose versus Pharmacokinetics: Although use of a shorter acting benzodiazepine hypnotic will decrease the possibility of morning hangover, dose is of equal…
- Sleep Disorders: Insomnia. Part 5 by: Kelly
November 9, 2009, 13:19
Antidepressant Drugs Sedating antidepressants have been used to induce sleep in doses lower than those generally used for depression in an attempt to avoid…
- Sleep Disorders: Insomnia. Part 4 by: Kelly
November 9, 2009, 13:16
Nonprescription Hypnotic Agents Antihistamines: Most over-the-counter drug treatments for insomnia contain the antihistamines diphenhydramine, doxylamine or…
- Sleep Disorders: Insomnia. Part 3 by: Kelly
November 9, 2009, 13:14
Nonpharmacologic Treatment Sleep experts universally recommend behavioral interventions, either alone or with adjunct medication, for the treatment of…
- Sleep Disorders: Insomnia. Part 2 by: Kelly
November 9, 2009, 13:13
Physiology of Sleep An understanding of normal sleep is essential in recognizing and effectively treating insomnia. Although individual sleep needs vary,…
- Sleep Disorders: Insomnia. Part 1 by: Kelly
November 9, 2009, 13:10
Newer agents with short duration of effect are changing the pharmacologic treatment of insomnia. Insomnia negatively affects as many as 10% of the U.S.…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 11 by: Kelly
November 9, 2009, 12:50
Legal Considerations By today's standards restraint and seclusion are to be used as safety measures, not as part of the treatment plan. According to the…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 10. Treatment by: Kelly
November 9, 2009, 12:49
Dosing and Choice of Dosage Form Table 4 describes dosing schedules for benzodiazepine and antipsychotics used to treat agitation and aggression. Oral…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 9. Treatment by: Kelly
November 9, 2009, 12:47
Atypical Antipsychotics vs. Typical Antipsychotics: Typical antipsychotics, particularly haloperidol, are still the most commonly used agents for treating…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 8. Treatment by: Kelly
November 9, 2009, 12:47
Atypical Antipsychotics: Atypical antipsychotics have become a standard of care in schizophrenia and they are increasingly being used as mood stabilizers.…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 7. Treatment by: Kelly
November 9, 2009, 12:45
Typical Antipsychotics: Strategies to treat agitation, aggression and psychosis have evolved since the introduction of chlorpromazine in 1952. During the…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 6. Treatment by: Kelly
November 9, 2009, 12:44
Selection of Appropriate Pharmacotherapy As previously stated, an important factor in selecting pharmacotherapy is knowing the underlying cause. For…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 5. Treatment by: Kelly
November 9, 2009, 12:43
Treatment Goals The first goal is to ensure safety of the patient and those around him. Secondly, symptoms need to be reduced to such a degree that safety…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 4 by: Kelly
November 9, 2009, 12:41
Patient Evaluation Once the safety of the patient and those around him is assured, a thorough evaluation is needed to identify contributing factors and to…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 2 by: Kelly
November 9, 2009, 12:33
CASE STUDY 1 KN is a 65-year-old woman admitted to a nursing home after her family can no longer care for her. She has Alzheimer's dementia and…
- Acute Agitation and Aggression in Psychiatric Illnesses. Part 1 by: Kelly
November 9, 2009, 12:30
Agitation and aggression are common symptoms in inpatient psychiatric settings, geriatric medicine and emergency room care. For example, some 10% of patients…
- Premenstrual Dysphoric Disorder. Part 8 by: Kelly
November 9, 2009, 12:13
THE PHARMACIST'S ROLE IN PMDD Premenstrual dysphoric disorder is a fairly recent discovery in women's health; yet, it currently costs the nation millions…
- Premenstrual Dysphoric Disorder. Part 7. Treatment by: Kelly
November 9, 2009, 12:11
As the pathophysiology of PMS and PMDD suggests, symptoms are associated with the elevation and decline of sex hormones during ovulation. As symptoms are not…
- Premenstrual Dysphoric Disorder. Part 6. Treatment by: Kelly
November 9, 2009, 12:09
Pharmacological Therapy for Emotional and Psychological Symptoms Often, nonpharmacological interventions are insufficient for adequate menstrual relief for…
- Premenstrual Dysphoric Disorder. Part 5. Treatment by: Kelly
November 9, 2009, 10:10
Once a patient meets the DSM-IV criteria and is diagnosed with premenstrual dysphoric disorder, therapy should be initiated. Consistent with many disorders…
- Premenstrual Dysphoric Disorder. Part 4 by: Kelly
November 9, 2009, 10:08
CRITERIA FOR DIAGNOSIS An estimated 3% to 8% of women of reproductive age suffer from premenstrual dysphoric disorder. Health care providers have made many…
- Premenstrual Dysphoric Disorder. Part 3 by: Kelly
November 9, 2009, 10:02
PMS/PMDD SYMPTOMS Premenstrual syndrome affects as many as 75% of women of reproductive age at some point in their life. However, studies have not defined…
- Premenstrual Dysphoric Disorder. Part 2 by: Kelly
November 9, 2009, 10:00
ETIOLOGY AND PATHOPHYSIOLOGY While many studies have focused on the predisposing factors related to premenstrual dysphoric disorder, the relative contributio…
- Premenstrual Dysphoric Disorder. Part 1 by: Kelly
November 9, 2009, 09:57
SM is a 24-year-old Asian Indian female who presents to her gynecologist with a chief complaint of "severe abdominal pain, breast tenderness, headaches, and…
- The Elderly: Insomnia, Depression, and Suicide Risk. Part 2 by: Kelly
November 9, 2009, 09:01
Depression, Morbidity, and Suicide Risk Why is it so important to assess the risk for depression in a senior with insomnia who may not feel comfortable…
- The Elderly: Insomnia, Depression, and Suicide Risk. Part 1 by: Kelly
November 9, 2009, 08:59
The notion that aging is a multifactorial process is commonly accepted. Many of the age-related changes that occur in a senior's nervous system have an impact…
- 5 Mental Disorders by: Kelly
November 9, 2009, 08:47
Many people need to be encouraged to seek help. Five leading mental disorders affect 10 million Americans, but many people, especially those suffering from…
- Work May Trigger Anxiety in Women by: Kelly
November 9, 2009, 08:43
Job stress found to cause a variety of mental ailments. Being overworked and underchallenged are job-related stress issues that for women may lead to…
- Insight Into Insomnia. Part 2. Pharmacotherapy by: Kelly
November 9, 2009, 08:40
Pharmacotherapy Drug therapy can be effective for short-term alleviation of insomnia but may not be sufficient for long-term management of chronic insomnia.…
- Insight Into Insomnia. Part 1 by: Kelly
November 9, 2009, 08:39
Insomnia is a subjective complaint of non-restorative sleep that may involve difficulty falling asleep, frequent or prolonged nocturnal awakenings, and early…
- Anxiety Disorders: Presentation by: Kelly
- Category: Question - Answer (47)
- Depression and Anxiety by: Kelly
July 17, 2010, 11:36
Question. I have been taking 0.1 mg of Synthroid and 200 mg Serzone daily for a little over six months. This seems to have improved my depression and anxiety…
- Augmenting Depression by: Kelly
May 11, 2010, 06:07
Question. I am veteran of SSRI poop-out. After more than four successful years on Zoloft, it stopped working. When tyrosine was added, it was effective for…
- Ambien and Depression by: Kelly
May 8, 2010, 06:04
Question. I take Luvox 150 mg per day for chronic depression and obsessive anger problems. My psychiatrist is concerned about my sleep habits, which have…
- Male Depression by: Kelly
May 5, 2010, 06:01
Question. I am attempting to research the area of male depression. Through my experience of working with clients and my current reading it, would seem clear…
- Suicide Attempt by: Kelly
April 17, 2010, 14:25
Question. Last month I attempted suicide. I still feel that my family would be better off without me, that there is no future for me, that there is no light at…
- Debating Prozac for a Child by: Kelly
April 14, 2010, 14:22
Question. After having exhausted many other avenues of treatment for my 6-year-old son, I feel confident that Prozac could change his life for the better. My…
- Homeopathic Treatment for Depression by: Kelly
April 3, 2010, 03:09
Question. Have there been any studies or support in the treatment of depression with homeopathic remedies? Answer. There is a good deal of interest in the…
- Is 5-HTP Safe? by: Kelly
March 28, 2010, 08:00
Question. Prime Time Live recently aired a story on treatment of depression, obesity and insomnia with 5-hydroxytryptophan (5-HTP). Is 5-HTP effective and…
- Depression and the medically ill by: Kelly
March 26, 2010, 07:58
Question. Are you aware of any fairly recent articles or publications dealing with the evaluation and treatment of depression in the medically ill, the…
- Prozac and Alcohol's Effects by: Kelly
March 24, 2010, 01:57
Question. I suffer from depression and have been on Prozac for a number of years now. It seems that after I have a few drinks, I notice a marked increase in my…
- Sex Drive and Prozac by: Kelly
March 22, 2010, 01:54
Question. I was diagnosed with major depression and have taken several antidepressants that do not work. I have been taking Prozac for about a month and am…
- Postpartum Depression and ECT by: Kelly
March 19, 2010, 01:16
Question. After I had a baby, I was diagnosed with postpartum depression and later postpartum psychosis. I tried many antidepressants and was also put on…
- Thorazine and Depression by: Kelly
January 27, 2010, 08:55
Question. I recently heard of the use of a low dose of Thorazine for the treatment of depression. Are you familiar with this treatment? Answer. I am not…
- Depression and Mood Music by: Kelly
January 26, 2010, 08:52
Question. I have read several articles that refer to the use of certain types of music that is supposed to help people who suffer from depression, but none of…
- Depression and Weight Gain by: Kelly
January 15, 2010, 08:09
Question. I used to take 100 mg of imipramine per day for depression. Then I was diagnosed with mixed bipolar and was switched to 750 mg Depakote and 225 mg of…
- Mental Health Professional with Depression by: Kelly
January 14, 2010, 07:20
Question. I am a mental health professional. However, I also find myself searching for information to console me personally. I have been diagnosed with major…
- Antidepressants as a Treatment for Bipolar Disorder by: Kelly
January 13, 2010, 07:41
Question. I have read reports that antidepressants prescribed for patients in the depressed phase of cyclothymic or bipolar II illness can (a) shorten the…
- Meds in the Second Trimester by: Kelly
January 12, 2010, 07:25
Question. My patient is in the second trimester of her pregnancy. She has panic disorder and depression. In the past, she responded well to Zoloft and…
- Meds for Depression and Anxiety by: Kelly
January 11, 2010, 07:48
Question. Do you have a list of drugs for depression, and non-addictive medications for anxiety? Tricyclics of the older vintage would be helpful. Answer. I…
- Zoloft and Pregnancy by: Kelly
January 10, 2010, 19:44
Question. I am a 40-year-old mother of two. A year ago I began taking Zoloft 150 mg per day. This medication has been a miracle for me. I am considering having…
- Tremors and Psychotropic Drugs by: Kelly
January 9, 2010, 19:39
Question. After five months of severe depression that was unresponsive to medication, I had ECT and came out of the depression. I was immediately started on…
- Prozac's Side Effects by: Kelly
January 8, 2010, 19:21
Question. I am on Prozac and suffer severe lower back pain and general aches and pains throughout the body especially the joints. Is there any link? Answer.…
- Excercise and Depression by: Kelly
January 7, 2010, 17:50
Question. I am recovering from alcohol and drug addiction and ocassionally suffer from depression. It seems to me that exercise helps, even if it is just…
- Immobilized by Depression by: Kelly
January 6, 2010, 17:47
Question. After using alcohol and amphetamines to dull my "bad feelings" for many years, I was diagnosed with clinical depression and put on antidepressants in…
- Depression and Stress by: Kelly
January 3, 2010, 17:40
Question: I have lots of pressures from school and recently began a job as well. I find that I am increasingly stressed out and depressed, even lethargic. I…
- Depression: Wellbutrin and Lamictal by: Kelly
January 1, 2010, 09:13
Question. My sister has been suffering for years with depression and is what has been termed a "difficult case." Generally, she tends not to react normally to…
- Paxil and Weight Gain by: Kelly
December 23, 2009, 09:10
Question. I have been taking 30 mg of Paxil daily for nearly two years. I have gained about 15 pounds that I can't drop even though I've increased my activity…
- Depression Medication Recommendation by: Kelly
December 18, 2009, 09:01
Question. I am writing this e-mail on behalf of my dad. He was diagnosed with depression about 7 years ago. ECT Treatments did not help. Although he has been…
- Mental Illness and Impotence by: Kelly
December 16, 2009, 08:56
Question. What mental illnesses may cause impotence? What psychotropics may contribute to the problem? Answer. Impotence, or erectile dysfunction , is…
- Antidepressants Exacerbating Hypertension by: Kelly
December 13, 2009, 09:07
Question. I have a problem with antidepressants exacerbating my hypertension. Are there any that don't increase blood pressure? Are there new antidepressants…
- Ruling out symptoms by: Kelly
December 12, 2009, 15:30
Question. I have a diabetic patient in her early 30s who is also exhibiting signs of anxiety and depression. She's on 100mg Glucophage as well as 100u Humulin…
- SSRI's Inhibitory Effects by: Kelly
December 4, 2009, 04:18
Question. Can you please give me your opinion on the P450 inhibitory effects of SSRIs, namely, fluoxetine, paroxetine, citalopram, sertraline and fluvoxamine?…
- Recurring Depression by: Kelly
December 3, 2009, 04:16
Question. I am a 33-year-old male who has suffered from major depression for about 10 years. I was also anorexic and bulimic around age 25. I have been in…
- "Old" vs. "New" Medications by: Kelly
November 28, 2009, 11:33
Question. My 18-year-old son was diagnosed schizophrenic two years ago. Currently hospitalized, he is receiving clozapine and Haldol as anti-psychotics and…
- Parkinson's and Depression by: Kelly
November 27, 2009, 03:35
Question. I have an 80-year-old relative with Parkinson's disease and depression who was started on Prozac with good initial effects on mood and energy levels.…
- Zyprexa (Olanzapine) and Depression by: Kelly
November 26, 2009, 03:20
Question. Has there been any testing yet of the efficacy of olanzapine (Zyprexa) for depression? Do you think its profile indicates that it might be a good…
- Depression and Sensitivity by: Kelly
November 25, 2009, 03:14
Question. I have had mild, chronic dysthymia since adolescence and have been helped greatly in the last few years by Prozac. I believe much of my depressive…
- Pit of Depression by: Kelly
November 21, 2009, 03:11
Question. My husband is depressive, on medication and seeing a psychiatrist. When he's in the "pit" he becomes incredibly needy. He has frequent panic attacks…
- Depression Meds and Side Effects by: Kelly
November 18, 2009, 13:20
Depression Meds and Side Effects Q. I am 19 and have experienced depression for over two years. My doctor recently prescribed Serzone, which caused severe…
- Episodic Depression Treatment by: Kelly
November 17, 2009, 13:13
Episodic Depression Treatment Q. I have been trying to deal with my depression, anxiety and posstraumatic stress disorder for 10 years. About nine months out…
- Depression and Inhalant Abuse by: Kelly
November 16, 2009, 13:43
Depression and Inhalant Abuse Q. I have a friend who inhaled gas three times in his youth. He is very smart and has a great memory, but has severe depression.…
- Discontinuing Depression Meds by: Kelly
November 15, 2009, 13:35
Discontinuing Depression Meds Q. I have had several bouts of depression in my life. Over the past six months, I have had recurrent periods of despondency and…
- Remeron and Weight Gain by: Kelly
November 14, 2009, 11:41
Question. My wife was diagnosed with depression and has tried various drug regimens. After trying many other meds, she recently began taking Remeron. Her…
- Luvox and Smoking by: Kelly
November 13, 2009, 06:04
Question. I have obsessive compulsive disorder and panic disorder. I was recently prescribed Luvox. I have had no adverse reactions, and my doctor insists that…
- New Therapy for Depression? by: Kelly
November 12, 2009, 17:34
Question. I've tried Prozac, Paxil, Zoloft, Pamelor, Effexor and Wellbutrin and I'm about ready to give up my antidepressant therapy! Nothing much happens,…
- Paxil vs. Luvox by: Kelly
November 11, 2009, 17:38
Question. I am taking 20mg of Paxil and am seeing a behavior therapist for obsessive-compulsive disorder. My obsessions have been greatly subdued and I feel I…
- Depression and Erectile Dysfunction by: Kelly
November 10, 2009, 17:47
Question. I have been depressed ever since my grandmother died three years ago. I have tried drugs and therapy, but nothing helps. I have no zest for life. My…
- Depression and Anxiety by: Kelly
- Category: Manuscripts (18)
- Drug Therapy in Psychiatry. Part 8 by: Kelly
December 31, 2009, 16:37
Observations obtained from carefully studied individual cases and from mass experiments would indicate that the tranquilizing drugs act by suppressing the…
- Drug Therapy in Psychiatry. Part 7 by: Kelly
December 30, 2009, 16:36
This brings up one of the most important issues on which no general agreement has been reached. A certain number of patients receiving the drugs function…
- Drug Therapy in Psychiatry. Part 6 by: Kelly
December 29, 2009, 16:35
We feel the following trends in the use of the tranquilizing drugs should be checked. First, patients should not receive a tranquilizing drug without proper…
- Drug Therapy in Psychiatry. Part 5 by: Kelly
December 28, 2009, 16:34
We would also like to emphasize that it is much more difficult to establish the maintenance dose of the patient than the primary therapeutic dose. We all use…
- Drug Therapy in Psychiatry. Part 4 by: Kelly
December 27, 2009, 16:33
The drugs, of course, are used not only in psychotic patients but in many neurotic patients. The tranquilizing drugs are prescribed in large quantities outside…
- Drug Therapy in Psychiatry. Part 3 by: Kelly
December 26, 2009, 16:33
At present we are using drugs in large numbers of patients. This does not necessarily mean that these patients should not have a physical and mental examination…
- Drug Therapy in Psychiatry. Part 2 by: Kelly
December 25, 2009, 16:32
Most of the reliable information on the action of these compounds relates to psychotic patients. A considerable literature also exists on then-use in neurotic…
- Drug Therapy in Psychiatry. Part 1 by: Kelly
December 24, 2009, 16:30
October 17, 1956 We should like to discuss several aspects of the problem from a clinical point of view, namely, what kind of drugs should be selected for…
- The Psychology of Depression. Part 10. Summary by: Kelly
December 9, 2009, 08:31
Depression is an affect which appears either in response to the loss of a love object or in anticipation of some act which would result in the loss of a love…
- The Psychology of Depression. Part 9. Management by: Kelly
December 8, 2009, 08:30
There are several forms of psychotherapy. In depression the simplest form of psychotherapy consists of the therapist's offering himself to the patient as a…
- The Psychology of Depression. Part 8. Management by: Kelly
December 8, 2009, 08:29
Cases of normal depression require no specific treatment since they usually resolve spontaneously in a period of a few weeks or months. The methods by which…
- The Psychology of Depression. Part 7. Mode of Resolution by: Kelly
December 7, 2009, 08:29
I have just described the device for facilitating recovery from depression which is called identification, that is, the mechanism by which the depressed…
- The Psychology of Depression. Part 6. Mode of Resolution by: Kelly
December 7, 2009, 08:28
The foregoing constitutes a fairly hopeless picture of depression and the number of vicious circles implied suggests that there is a spontaneous tendency for…
- The Psychology of Depression. Part 5. The Role of Aggression and Guilt by: Kelly
December 6, 2009, 08:27
To return to the subject of pathologic depression, we may explain the persistence of aggression after the depressive reaction has set in, as an instance of the…
- The Psychology of Depression. Part 4. The Role of Aggression and Guilt by: Kelly
December 6, 2009, 08:27
A frequent component of normal depression and a constant component of pathologic depression is an aggressive tendency. Considering the formulation offered…
- The Psychology of Depression. Part 3. Functions and Nature by: Kelly
December 5, 2009, 08:26
However the situation is less simple in cases of neurotic or psychotic depression. Here we are often able to see no obvious loss, or a loss which is trivial.…
- The Psychology of Depression. Part 2. Functions and Nature by: Kelly
December 5, 2009, 08:25
Since depression is so obviously a component of normal daily life one may assume that it has a function. This problem may be approached by first considering…
- The Psychology of Depression. Part 1 by: Kelly
December 4, 2009, 08:25
November 9, 1954 Depression is one of the common affective phenomena of daily living and it is also one of the most common symptoms of serious psychic…
- Drug Therapy in Psychiatry. Part 8 by: Kelly
- Category: Images Diagrams Tables (14)
- Histamine by: Kelly
January 2, 2010, 11:15
The distribution in the human brain of neurons and their projections (arrows) containing histamine.
- Serotonin by: Kelly
January 1, 2010, 11:13
The distribution in the human brain of neurons and their projections (arrows) containing serotonin.
- Bladder - Urinary Retention by: Kelly
December 30, 2009, 16:37
Noradrenergic innervation of the urinary tract via sympathetic neurons leaving the spinal cord regulates bladder emptying via alpha 1 receptors.
- Heart - Tachycardia by: Kelly
December 29, 2009, 16:37
Noradrenergic innervation of the heart via sympathic neurons leaving the spinal cord regulates cardiovascular function, including heart rate, via beta 1…
- Brainstem - Blood Pressure by: Kelly
December 28, 2009, 16:37
Brainstem norepinephrine in cardiovascular centers controls blood pressure.
- Cerebellum - Tremor by: Kelly
December 27, 2009, 16:37
The noradrenergic projection from the locus coeruleus to the cerebellum may mediate motor movements, especially tremor.
- Limbic - Energy Level, Agitation, Emotions by: Kelly
December 26, 2009, 16:37
The noradrenergic projection from the locus coeruleus to limbic cortex may mediate emotions, as well as energy, fatigue, and psychomotor agitation or…
- Frontal 2 - Attention by: Kelly
December 25, 2009, 16:37
Other noradrenergic projections from the locus coeruleus to frontal cortex are thought to mediate the effects of norepinephrine on attention, concentration,…
- Frontal 1 - Depression by: Kelly
December 24, 2009, 16:37
Some noradrenergic projections from the locus coeruleus to frontal cortex are thought to be responsible for the regulatory actions of norepinephrine on…
- Norepinephrine by: Kelly
December 24, 2009, 00:09
The distribution in the human brain of neurons and their projections (arrows) containing catecholamine neurotransmitters.
- Epinephrine by: Kelly
December 23, 2009, 01:08
The distribution in the human brain of neurons and their projections (arrows) containing catecholamine neurotransmitters.
- Dopamine by: Kelly
December 22, 2009, 22:05
The distribution in the human brain of neurons and their projections (arrows) containing catecholamine neurotransmitters.
- Somatotopic organization of sensory information by: Kelly
December 18, 2009, 22:32
(Top) The locations of primary and secondary somatosensory cortical areas on the lateral surface of the brain. (Bottom) Cortical representation of…
- Gross anatomy of the forebrain by: Kelly
December 17, 2009, 22:25
(A) Cerebral hemisphere surface anatomy, showing the four lobes of the brain and the major sulci and gyri. The ventricular system and basal ganglia can…
- Histamine by: Kelly
- Category: Treatment of Depression (2)
- Depression Interventions Effective by: Kelly
January 28, 2010, 11:16
Depression treatment in the United States has been getting a bad name in a number of quarters recently. Patients who responded to Caredata.com's 1999 Commercial…
- St. John’s Wort and the Treatment of Depression by: Kelly
January 24, 2010, 05:25
Historically, St. John’s wort has been used as an herbal remedy for depression, anxiety, diuresis, gastritis and insomnia. Recent studies demonstrate that…
- Depression Interventions Effective by: Kelly
- Category: Management (7)
- Management of Resistant Depression. Prophylaxis. Conclusion by: Kelly
March 10, 2010, 18:55
Prophylaxis Discussing prevention of relapse or recurrence of major depression is beyond the scope of this paper but is clearly important. Long-term use of…
- Management of Resistant Depression. Less Approaches. Treatment Resistance. by: Kelly
March 8, 2010, 18:53
Less common approaches. Many less commonly used antidepressant therapies are supported by anecdotal evidence only. They include light therapy (non-seasonal…
- Management of treatment-resistant depression: strategies for treatment by: Kelly
March 6, 2010, 18:50
Common strategies for treatment resistance. Electroconvulsive therapy An important and effective treatment for depression, electroconvulsive therapy (ECT) is…
- Management of treatment-resistant depression: Switching antidepressants by: Kelly
March 4, 2010, 18:47
If lithium augmentation is ineffective, it should be discontinued and the antidepressant changed (Table 5). A lack of response to one of the newer…
- Management of treatment-resistant depression (TRD) by: Kelly
March 2, 2010, 18:46
Major depression is best managed through a treatment algorithm. The more resistant to treatment a patient's illness is, the further treatment proceeds through…
- Management of Resistant Depression. Factors. Treatment Adequate. by: Kelly
February 28, 2010, 01:20
Are there underlying physical factors? Many physical diseases present with depressive symptoms or complicate depressive illness (Table 2). Some of these…
- Management of Resistant Depression. Subtypes of Depression by: Kelly
February 26, 2010, 01:16
More than 20% of patients with major depression have not recovered after 2 years and, of those who do initially recover, 20% suffer a relapse 1 year later.…
- Management of Resistant Depression. Prophylaxis. Conclusion by: Kelly
- Category: Research Digest (5)
- Antidepressant Gets High Marks by: Kelly
May 2, 2010, 05:44
Results from several clinical studies designed to assess the effectiveness and tolerability of Reboxetine (Edronax), a new antidepressant agent, were announced…
- Risk of Depression in Young Women by: Kelly
April 30, 2010, 05:43
A recent study sought to examine the risk of depression among young women. Researchers at the University of California, Los Angeles, studied the psychiatric…
- Effects of Some Antidepressants Depressing by: Kelly
April 27, 2010, 05:40
Sexual dysfunction associated with antidepressants may be more prevalent than previously believed, according to researchers at Case Western Reserve University…
- Why Epileptics Suffer from Depression by: Kelly
April 24, 2010, 05:38
Having epilepsy seems to increase the likelihood that you'll suffer from chronic depression and multiplies the risk for suicide by five times. Researchers from…
- Depression Takes Heavy Toll on Diabetics by: Kelly
April 21, 2010, 05:35
Recent studies indicate that depression precedes Type II diabetes in 90 percent of people with both illnesses. What does that really mean to you? Researchers…
- Antidepressant Gets High Marks by: Kelly
- Category: SSRIs (6)
- SSRIs in anxious depression: Fluvoxamine by: Kelly
October 13, 2010, 09:59
Houck and Stankovic (1997) performed an 8-week open-label trial of fluvoxamine (Luvox) in 15 outpatients diagnosed as having mixed anxiety depression (MAD).…
- SSRIs in anxious depression: Sertraline by: Kelly
October 9, 2010, 09:58
Carrasco and colleagues (1997) treated 36 patients with mixed anxiety-depression (ICD-10) with sertraline (Zoloft) in an open trial. Concomitant benzodiazepines…
- SSRIs in anxious depression: Paroxetine by: Kelly
October 7, 2010, 09:57
Paroxetine (Paxil) has produced some of the most striking data showing superior efficacy on anxiety symptoms within depression compared with other antidepressan…
- SSRIs in anxious depression: Fluoxetine by: Kelly
October 3, 2010, 09:52
The efficacy of fluoxetine (Prozac) in anxious depression was reported by Montgomery (1989) in an analysis of the pooled data of those patients who entered…
- SSRIs in anxious depression by: Kelly
October 1, 2010, 09:49
Most patients suffering from major depression have anxiety symptoms as well as depressive symptoms and these commonly occurring anxiety symptoms are normally…
- SSRIs. Forest Laboratories by: Kelly
May 21, 2010, 07:19
Definition of Depression A diagnosis of major depressive disorder is made if an individual has five or more of the following symptoms during the same two-week…
- SSRIs in anxious depression: Fluvoxamine by: Kelly
- Category: Medical Practice (7)
- Interpersonal Psychotherapy by: Kelly
May 25, 2011, 09:52
Interpersonal Psychotherapy (IPT) is a time-limited psychotherapy specified in a manual and tested in numerous clinical trials that have established its…
- Therapeutic Lifestyle Change by: Kelly
May 24, 2011, 12:19
Therapeutic lifestyle change (TLC) is a 14-week behavioral intervention for depression based on a set of six principal lifestyle elements of established…
- Exercise and Depression by: Kelly
May 24, 2011, 12:07
Exercise may have an important role in the prevention and treatment of major depressive disorder. Available research evidence suggests that exercise reduces a…
- Fussy Jane by: Kelly
November 21, 2010, 15:28
• present an overview of obsessive-compulsive disorder and the associated symptoms; • describe its pathophysiology; • explain the pharmacological…
- Continual concerns for Mr Watson by: Kelly
November 14, 2010, 14:48
• present an overview of manic depressive disorder (bipolar affective disorder) and the associated symptoms; • describe its pathophysiology and…
- A dangerous father? by: Kelly
November 7, 2010, 14:42
• present an overview of mania, its aetiology and associated symptoms; • outline a possible connection between the use of antidepressants and the…
- A mother's loss by: Kelly
November 2, 2010, 14:33
• describe the signs and symptoms associated with this disorder; • describe the underlying pathophysiology of the disorder presented; • outline…
- Interpersonal Psychotherapy by: Kelly
- Category: Patient Treatment Manual (27)
- Posttraumatic Stress Disorder by: Kelly
August 15, 2011, 16:47
This Manual is both a guide to treatment and a workbook for persons who suffer from posttraumatic stress disorder. During treatment, it is a workbook in which…
- Managing Anxiety and Distress by: Kelly
August 15, 2011, 16:45
The next step is to help you to feel more in control of your reactions. We will do this in several parts. First, there are many simple things you can do in…
- Exposure Therapy: Confronting Feared Situations by: Kelly
August 15, 2011, 16:44
The next part of treatment is the most difficult and painful - confronting the feared situations and traumatic memories. It is also the most important. Your…
- Exposure Therapy: Confronting the Memories by: Kelly
August 15, 2011, 16:43
A form of exposure therapy is also used to treat distressing memories of the trauma. We call it "imaginal exposure". In Section 5, we talked about confronting…
- Generalized Anxiety Disorder by: Kelly
August 15, 2011, 16:40
This Manual is both a guide to treatment and a workbook for people who suffer from generalized anxiety disorder. During treatment, it is a workbook in which…
- Relaxation Strategies:Generalized Anxiety Disorder by: Kelly
August 15, 2011, 16:38
What is relaxation training? Relaxation is the voluntary letting go of tension. This tension can be physical tension in the muscles or it can be mental, or…
- Thinking Strategies by: Kelly
August 15, 2011, 16:36
Humans are thinking, feeling, and behaving beings. These three aspects of our make-up interact with each other. However, thoughts can often go unrecognized and…
- Managing Worry by: Kelly
August 15, 2011, 16:34
Individuals with generalized anxiety worry a lot. These worries tend to center on everyday things; we all worry to some extent about problems that might arise…
- Structured Problem Solving by: Kelly
August 15, 2011, 16:32
Our lives are full of problems to be solved, ranging from major life crises to the more mundane hassles of our day-to-day lives. However, no matter how small…
- Obsessive-Compulsive Disorder by: Kelly
August 15, 2011, 16:29
This Manual is both a guide to treatment and a workbook for persons who suffer from obsessive-compulsive disorder. During treatment, it is a workbook in…
- Specific Phobias by: Kelly
August 15, 2011, 16:23
This Manual is both a guide to treatment and a workbook for persons who suffer from specific phobias. During treatment, it is a workbook in which individuals…
- Relaxation training: Specific Phobias by: Kelly
August 15, 2011, 16:20
The importance of relaxation training Human beings have a built-in response to threat or stress known as the flight or fight response. Part of this flight or…
- Graded Exposure: Specific Phobias by: Kelly
August 15, 2011, 16:18
One of the hallmarks of a phobia is that the feared object or situation is avoided or endured with considerable distress. Remember that the sorts of avoidance…
- Thinking Straight by: Kelly
August 15, 2011, 16:16
This part of the program is designed to help you to control the kinds of thoughts that occur when you are in the presence of something you fear. These thoughts…
- Blood and Injury Phobia by: Kelly
August 15, 2011, 16:15
Fear and fainting Blood and injury phobias are relatively common, being found in about 4% of people. People with blood and injury phobias can be divided into…
- Social Phobia by: Kelly
August 15, 2011, 16:10
This Manual is both a guide to treatment and a workbook for people who suffer from social phobia. During treatment, it is a workbook in which individuals can…
- The Nature of Anxiety by: Kelly
August 15, 2011, 16:09
Anxiety is part of an automatic response to threat that all animals share. It is known as the flight or fight response. A series of physiological changes is…
- Anxiety-Management Strategies by: Kelly
August 15, 2011, 16:05
By paying attention to these factors you can help to reduce your level of arousal - the degree of tension and alertness you feel - when this is excessive for…
- Cognitive Therapy for Social Phobia by: Kelly
August 15, 2011, 16:03
People with social phobia experience anxiety in the company of others. However, there are marked variations between individuals in terms of the degree of…
- Graded Exposure by: Kelly
August 15, 2011, 15:58
Ultimately, a phobia can be overcome only when an individual confronts his or her fears. This is called "exposure" to the feared situation. The most commonly…
- Assertiveness by: Kelly
August 15, 2011, 15:56
What is assertiveness? Healthy assertion - assertiveness - is about choice and communication. It is the making of active choices about what to do and say. It…
- Panic Disorder and Agoraphobia by: Kelly
August 15, 2011, 15:44
This Manual is both a guide to treatment and a workbook for persons who suffer from panic disorder and agoraphobia. During treatment, it is a workbook in which…
- Control of Hyperventilation by: Kelly
August 15, 2011, 15:41
Recognizing hyperventilation The first step in preventing and controlling hyperventilation is to recognize how and when you overbreathe. Try monitoring…
- Graded Exposure by: Kelly
August 15, 2011, 15:34
When a panic attack occurs for the first time in a certain situation, most people believe that, should they find themselves in that same situation again, they…
- Thinking Straight by: Kelly
August 15, 2011, 15:31
This part of the program will help you to control the thoughts that accompany and promote anxiety. This will be done by learning to label situations more…
- Producing the Panic Sensations by: Kelly
August 15, 2011, 15:29
One of the elements central to panic is the fearful reaction to bodily sensations, such as a pounding heart, dizziness, etc. We deal with this subject towards…
- More About Thinking Straight by: Kelly
August 15, 2011, 15:25
Having discussed previously how unhelpful thoughts can be identified, challenged, and disputed we shall consider another method. Rather than engaging in a…
- Posttraumatic Stress Disorder by: Kelly
