Question. Have there been any studies or support in the treatment of depression with homeopathic remedies?

Answer. There is a good deal of interest in the use of herbal remedies for the treatment of depression, as well as in the use of naturally-occurring precursors (building blocks) of various brain chemicals, called amino acids. The most persuasive literature on herbal treatments involves the use of St. John’s Wort (hypericum perforatum); this is reviewed in an article by Ken Bender in the October 1996 Psychiatric Times. German researchers recently published an analysis of 23 trials of this herb, in a total of over 1,700 patients with mild to moderate depression, and concluded that it is superior to placebo and comparable to standard antidepressants, while producing fewer side effects; however, there is very little in the American literature on this and I would reserve judgment regarding severe or psychotic types of depression.

Many studies have suggested that amino acids – which are naturally occurring building blocks of proteins – may be useful as adjunctive treatments of depression. L-tryptophan, phenylalanine and tyrosine have all shown some promise, though few controlled studies exist. (L-tryptophan was removed from the U.S. market some years ago due to a contaminant.) If you want more information on natural approaches to illness, you may want to subscribe to the Review of Natural Products, published by Facts and Comparisons, 111 West Port Plaza, Suite 300, St. Louis, MO 63146-9811. But remember, the word “natural” does not always mean safe. Many herbs and plant substances found in health food stores – and not approved by the FDA for use in any illnesses – contain compounds that can produce serious side effects. Thus, it is important to check with your doctor before setting out on any kind of self-medication venture using natural products.

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