Archives for SSRIs
SSRIs in anxious depression: Fluvoxamine
Posted By Kelly On Wednesday, October 13th 2010 under: SSRIs Tags: Luvox
Houck and Stankovic (1997) performed an 8-week open-label trial of fluvoxamine (Luvox) in 15 outpatients diagnosed as having mixed anxiety depression (MAD). Baseline scores on the HAMD indicated moderate degrees of both anxiety and depression prior to treatment. The patients experienced significant improvement in both areas (p < 0.001).
Fluvoxamine has also been compared with benzodiazepines in several relevant clinical trials. Laws and colleagues (1990) conducted a 6-week, multi-centre double-blind comparison ... Read More
SSRIs in anxious depression: Sertraline
Posted By Kelly On Saturday, October 9th 2010 under: SSRIs Tags: sertraline-latest-trial, Zoloft
Carrasco and colleagues (1997) treated 36 patients with mixed anxiety-depression (ICD-10) with sertraline (Zoloft) in an open trial. Concomitant benzodiazepines were not allowed during the study. Twenty-seven patients (75%) were rated as marked or moderate responders by the end of the 8-week study period.
A meta-analysis compared the efficacy of sertraline (Zoloft) (N = 218), amitriptyline (N = 214), and placebo (N = 214) in two outpatient studies. The results showed ... Read More
SSRIs in anxious depression: Paroxetine
Posted By Kelly On Thursday, October 7th 2010 under: SSRIs, Uncategorized Tags: Paxil
Paroxetine (Paxil) has produced some of the most striking data showing superior efficacy on anxiety symptoms within depression compared with other antidepressants. It has been perceived as one of the more "anxiolytic of the SSRIs" and this has been recognized in the granting of specific labelling for both depression and depression and anxiety in some countries, including the UK. More recently the granting of licenses for OCD, panic disorder, social ... Read More
SSRIs in anxious depression: Fluoxetine
Posted By Kelly On Sunday, October 3rd 2010 under: SSRIs Tags: Prozac
The efficacy of fluoxetine (Prozac) in anxious depression was reported by Montgomery (1989) in an analysis of the pooled data of those patients who entered studies with moderate or severe degrees of agitation. In a small study, Jouvent and colleagues (1989) reported that fluoxetine (Prozac) was more effective in anxious-impulsive patients than in those with a blunted affect. Several large-scale meta-analyses of fluoxetine (Prozac) data have reported findings supporting the ... Read More
SSRIs in anxious depression
Posted By Kelly On Friday, October 1st 2010 under: SSRIs Tags: Luvox, Paxil, Prozac, salipax, Selective serotonin reuptake inhibitors (SSRIs), Zoloft
Most patients suffering from major depression have anxiety symptoms as well as depressive symptoms and these commonly occurring anxiety symptoms are normally regarded as part of the depressive disorder. The presence of anxiety symptoms does not lead necessarily to a separate diagnosis of an anxiety disorder and indeed widely used depression rating scales include a large number of items devoted to anxiety symptoms, which contribute to the assessment of overall ... Read More
SSRIs. Forest Laboratories
Posted By Kelly On Friday, May 21st 2010 under: SSRIs Tags: Celexa, Lexapro
Definition of Depression
A diagnosis of major depressive disorder is made if an individual has five or more of the following symptoms during the same two-week period. The symptoms may vary from person to person but often include:
a persistent sad mood
loss of interest or pleasure in activities that were once enjoyed
significant change in appetite or body weight
difficulty sleeping or oversleeping
physical slowing or agitation
loss of energy
feelings of worthlessness or inappropriate guilt
difficulty thinking ... Read More