Depression Symptoms Treatment
Archive for the ‘Zyprexa (olanzapine)’ Category
Brand Name Drug: Zyprexa
Active Ingredient Drug: olanzapine
Indication: Treatment of manic depression/bipolar disorder
Company Name: Eli Lilly and Company
Introduction
Manic depression, also called bipolar disorder, afflicts some 4 million Americans. Characterized by severe mood swings between incredible elation and deep depression, the disorder has been difficult to treat. Many patients either do not respond to drug therapy or stop taking their medication because of unwanted side effects.
Now a new drug has entered the arena: Zyprexa (olanzapine), manufactured by Eli Lilly. Zyprexa had already been approved for the treatment of schizophrenia, and recently got the green light from the FDA for use in patients with manic depression.
Clinical Study Results
Studies evaluating the effectiveness of the drug in patients with acute mania showed that those who took Zyprexa (olanzapine) achieved a significantly greater improvement in their symptoms than patients who received a placebo. Other studies have shown that Zyprexa is as effective as lithium, another agent commonly used to treat manic depression.
What Read more [...]
Zyprexa
Brand Name:
Zyprexa
Active Ingredient:
olanzapine
Indication:
Treatment of manic depression (bipolar disorder); also approved for schizophrenia
Company Name:
Eli Lilly and Company
Availability:
Approved in 1997 for schizophrenia and on March 20, 2000 for manic depression (bipolar disorder)
Introduction
Bipolar disorder is a lifelong psychiatric disorder that features mood swings between mania and depression, and afflicts some 4 million Americans. Although lithium, valproate, carbamazepine, and antipsychotics have been prescribed to treat the disorder, many patients do not respond to these treatments or stop taking them due to unwanted side effects. Now there is another drug available for these patients: Eli Lilly received FDA approval to market Zyprexa (olanzapine) - a drug originally approved for schizophrenia - for the treatment of manic depression.
How It Works
Zyprexa is an antipsychotic drug. Although the exact mechanism of action is unknown, it is proposed that the drug's activity is mediated through a combination of dopamine and serotonin type 2 (5-HT2) antagonism, Read more [...]