Depression Symptoms Treatment » Zoloft (Sertraline)

Sertraline Hydrochlonde

admin — Sat, 25 Dec 2010 06:05:44 +0000

Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: CP-51974-01; CP-51974-1; Sertralina, hidrocloruro de BAN: Sertraline Hydrochloride [BANM] USAN: Sertraline Hydrochloride INN: Sertraline Hydrochloride [rINNM (en)] INN: Hidrocloruro de sertralina [rINNM (es)] INN: Sertraline, Chlorhydrate de [rINNM (fr)] INN: Sertralini Hydrochloridum [rINNM (la)] INN: Сертралина Гидрохлорид [rINNM (ru)] Chemical name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl(methyl)amine hydrochloride Molecular formula: C17H17Cl2N,HCl =342.7 CAS: 79617-96-2 (sertraline); 79559-97-0 (sertraline hydrochloride) ATC code: N06AB06 Note. The following terms have been used as 'street names' or slang names for various forms of sertraline: Z's Zloft Zoomers. Pharmacopoeias. In Europe. European Pharmacopoeia, 6th ed. (Sertraline Hydrochlonde). A white or almost white, crystalline powder, ft exhibits polymorphism. Slightly soluble in water freely soluble in anhydrous alcohol Read more [...]

Drug sertraline (Zoloft) therapy for controlling symptoms of premenstrual syndrome

admin — Tue, 19 Jan 2010 01:59:49 +0000

A new study suggests that the antidepressant drug sertraline (Zoloft), from Pfizer Inc., may be effective in controlling symptoms of premenstrual syndrome (PMS). * Researchers at Scott & White Memorial Hospital in Temple, Texas, randomized 57 women diagnosed with moderate-to-severe premenstrual syndrome (PMS) to treatment with Zoloft or a placebo at 14 days prior to the expected onset of menses to collect data; participants were switched to the other therapy after two months. * Found that Zoloft-treated women showed significant improvement in PMS-related symptoms, compared to placebo recipients, and that while most women improved in their first cyle of Zoloft therapy, the benefits were greater after the second cycle of treatment. * There were no serious side effects among Zoloft users, but about 10% of women complained of insomnia. * Researchers say that since Zoloft is eliminated from the body in about 26 hours it is suitable for short-term use. - authors note that further study is needed to confirm the findings and to assess the long-term effects of Zoloft therapy in women with premenstrual Read more [...]

The antidepressant drug sertraline (Zoloft) may be effective in panic disorder

admin — Mon, 18 Jan 2010 14:49:51 +0000

A recent study concludes that the antidepressant drug Zoloft (Sertraline) appears to be effective in reducing the number of panic attacks in patients with panic disorder.

* Researchers at Detroit’s Wayne State University randomized 168 patients with panic disorder to receive either sertraline or a placebo for 10 weeks to collect data.

* Found that the average number of panic attacks suffered weekly by patients treated with sertraline dropped 88%, compared to a 53% drop seen in placebo recipients. – authors further note that patients treated with sertraline showed significant improvements in measures of quality of life enjoyment and on personal assessments of the severity of their illness.

* The report notes that sertraline treatment was not associated with “jitteriness,” which is a common side-effect of older antidepressants used to treat panic disorder.

Drug sertraline (Zoloft) therapy for controlling symptoms of premenstrual syndrome A new study suggests that the antidepressant drug sertraline (Zoloft), from Pfizer Inc., may be effective in controlling symptoms of premenstrual syndrome (PMS). * Researchers at Scott & White Memorial Hospital in Temple, Texas, randomized 57 women diagnosed with moderate-to-severe premenstrual syndrome (PMS) to treatment ...
SSRIs in anxious depression: Sertraline Carrasco and colleagues (1997) treated 36 patients with mixed anxiety-depression (ICD-10) with sertraline (Zoloft) in an open trial. Concomitant benzodiazepines were not allowed during the study. Twenty-seven patients (75%) were rated as marked or moderate responders by the end of the 8-week study period. A ...
SSRIs and Treatment of Panic Disorder. Part 2 Selective Serotonin Reuptake Inhibitors Most recently, the selective serotonin reuptake inhibitors (SSRIs) have provided an alternative to the older pharmacologic treatments. Although paroxetine and, very recently, sertraline have FDA-approved indications for the treatment of panic disorder, a significant body of literature exists, as well, for ...
Zoloft (Setraline): Review of Systems Cardiovascular In the current Zoloft labeling, it is noted that analysis of ECG data from 774 patients receiving sertraline in clinical trials revealed no pattern of significant ECG abnormalities. In this database, cardiovascular adverse experiences were not important causes of discontinuation from treatment and were not ...
Effects of Some Antidepressants Depressing Sexual dysfunction associated with antidepressants may be more prevalent than previously believed, according to researchers at Case Western Reserve University School of Medicine. The American Psychiatric Association reports that depression, a serious mental health problem affecting more than 17 million Americans, is a highly treatable ...

Zoloft for Post-Traumatic Stress Disorder

admin — Thu, 12 Nov 2009 16:39:45 +0000

Zoloft Brand Name: Zoloft Active Ingredient: sertraline hydrochloride Indication: Treatment of posttraumatic stress disorder; also indicated for depression, obsessive-compulsive disorder, and panic disorder Company Name: Pfizer Inc. Availability: This new indication was approved by FDA on December 7, 1999 Introduction More than 100 million prescriptions for Pfizer's Zoloft have been written since its launch in 1992, helping patients with depression, obsessive-compulsive disorder, and panic disorder. Now Zoloft is the first medication to be approved for treating post-traumatic stress disorder (PTSD), which may develop in an individual following any extreme traumatic event in which there was threatened death or serious injury, and the person's response involved intense fear, helplessness, or horror. Such events may include physical and sexual abuse and natural disasters. Some 50% of the general population is exposed to a traumatic event in their lifetimes, and 10% to 20% of those people develop PTSD. The disorder is twice as common in women as in men, and is associated with symptoms Read more [...]

Zoloft Eases Trauma’s Aftermath

admin — Thu, 12 Nov 2009 02:27:54 +0000

Helps 3 in 5 people even without psychotherapy The antidepressant drug sertraline can provide relief from the disabling emotions that follow a traumatic experience, a study shows. The study was instrumental in gaining Food and Drug Administration approval for sertraline to treat post-traumatic stress disorder (PTSD), says Dr. Jonathan R.T. Davidson, a professor of psychiatry at Duke University Medical Center who directed the trial. Marketed as Zoloft, it is the only drug in its class to have FDA approval for treatment of PTSD. While post-traumatic stress disorder was first given formal designation in 1980, it was often seen before that in military personnel who experienced the hells of war ("shell shock" was a common term). It can cause severe psychological problems, including flashbacks to the traumatic experience, depression, emotional numbness, alcoholism and panic attacks, increasing the probability of suicide. Its physical symptoms can include stomach trouble, crippling headaches and a feeling of perpetual exhaustion. Those problems can last for up to five years without treatment. Any act Read more [...]

Zoloft Helps premenstrual syndrome (PMS)

admin — Mon, 09 Nov 2009 06:34:24 +0000

Antidepressant relieves severe menstrual symptoms.

Women suffering from a severe form of premenstrual syndrome were helped by Zoloft, according to a study of 200 women in a dozen medical centers. About 62% of the women showed “much or very much improvement” compared with 34% given a placebo. The PMS symptoms experienced by the women included poor concentration, depression and anger.

Drug sertraline (Zoloft) therapy for controlling symptoms of premenstrual syndrome A new study suggests that the antidepressant drug sertraline (Zoloft), from Pfizer Inc., may be effective in controlling symptoms of premenstrual syndrome (PMS). * Researchers at Scott & White Memorial Hospital in Temple, Texas, randomized 57 women diagnosed with moderate-to-severe premenstrual syndrome (PMS) to treatment ...
Prozac Lessens Premenstrual Dysphoric Disorder Symptoms Drug lessens severity of premenstrual dysphoria. Intermittent dosages of fluoxetine (Prozac/Lilly) given during the luteal phase of the menstrual cycle may help women suffering from PMDD (premenstrual dysphoric disorder), studies suggest. Premenstrual dysphoric disorder, a severe variant of premenstrual syndrome, affects 3%-5% of women during ...
Premenstrual Dysphoric Disorder. Part 3 PMS/PMDD SYMPTOMS Premenstrual syndrome affects as many as 75% of women of reproductive age at some point in their life. However, studies have not defined an exact age-group or time course for this syndrome to occur. But one study suggests that the 25 to ...
Premenstrual Dysphoric Disorder. Part 1 SM is a 24-year-old Asian Indian female who presents to her gynecologist with a chief complaint of "severe abdominal pain, breast tenderness, headaches, and weight gain" during her menstrual cycle. She states that her cramps feel like "pins through her stomach." Her boyfriend states ...
Abbreviation AE - Adverse Event CRF - Case Report Form DCT - Demethylcitalopram DDCT - Didemethyl Metabolite DSU - Drug Surveillance Unit ECG - Electrocardiogram ISS - Integrated Summary of Safety PMDD - Premenstrual Dysphoric Disorder PMS - Premenstrual Syndrome SAE - Serious Adverse Event SIADH - Syndrome of Inappropriate Antidiuretic Hormone SSRI - Selective Serotonin ...

Zoloft and premenstrual dysphoric disorder

admin — Sun, 04 Oct 2009 16:38:10 +0000

Research question Is sertraline (Zoloft) effective at improving the symptoms and reducing the functional impairment associated with premenstrual dysphoric disorder (PMDD)? Type of article and design Prospective, multicentre, double-blind, randomized placebo-controlled trial. Relevance to family physicians As defined by DSM-IV criteria, PMDD has a group of physical and behavioural symptoms that occur during the premenstrual period and are severe enough to interfere with work, usual activities, and relationships. Premenstrual syndrome (PMS), on the other hand, has milder physical and behavioural symptoms (breast tenderness, bloating, headache, and minor mood changes). Studies have documented that about 20% to 40% of women experience premenstrual symptoms, but only about 4% to 8% of women have PMDD. The quality of life of patients with PMDD would improve substantially if medical therapy could alleviate its physical and psychological symptoms and reduce functional impairment. Recent clinical trials suggest that progesterone (Prometrium) or oral contraceptives are no more effective than Read more [...]

Zoloft (Setraline): Review of Systems

admin — Sat, 26 Sep 2009 11:51:01 +0000

Cardiovascular In the current Zoloft labeling, it is noted that analysis of ECG data from 774 patients receiving sertraline in clinical trials revealed no pattern of significant ECG abnormalities. In this database, cardiovascular adverse experiences were not important causes of discontinuation from treatment and were not among the common, drug related adverse events. A slight decrease in mean heart rate was observed, as noted above. No serious adverse events involved the cardiovascular system. One Japanese subject withdrew for palpitations; two subjects withdrew for hypertension but both had previous histories of high blood pressure, and one subject withdrew for tachycardia. These data do not provide evidence that sertraline treatment of panic disorder patients presents any unique cardiovascular risk. Gastrointestinal Nausea, diarrhea and dyspepsia are recognized adverse reactions to sertraline treatment, as described in the current Zoloft labeling. In these clinical trials, no serious adverse events involved the gastrointestinal system. There were a total of 27 adverse gastrointestinal events Read more [...]