Treatment of Partially Responsive and Nonresponsive Patients. 1
Posted By Kelly On Saturday, June 19th 2010 under: Antidepressants Tags: Atypical antidepressants, MAOIs, SNRIs, SSRIs, TCAs
There is little benefit in making treatment changes before three weeks, other than to mitigate side effects. Changes in treatment strategy should be considered after the physician is satisfied that the patient has been treated with an adequate dosage of the antidepressant for an adequate time, with current medications increased to the limit of side effect tolerance.
In patients showing an inadequate response after a reasonable time, the decision is either ... Read More
Drug Selection and Initiation of Treatment for Major Depression. Treatment
Posted By Kelly On Tuesday, June 15th 2010 under: Antidepressants Tags: Atypical antidepressants, MAOIs, SNRIs, SSRIs, TCAs
Initiation of Treatment
Starting doses, titration schemes, and target doses for commonly-used tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and other agents are shown in Table: Starting Dose, Titration Steps, and Target Doses for Common Antidepressants. Once medication is initiated, it should be gradually increased to therapeutic levels by titration.
TCAs are usually started at a relatively low dose; these low doses are preferred in elderly patients. ... Read More
Drug Selection and Initiation of Treatment for Major Depression
Posted By Kelly On Monday, June 14th 2010 under: Antidepressants Tags: Atypical antidepressants, MAOIs, SNRIs, SSRIs, TCAs
On average, all antidepressants are equally effective. Without a personal or family history of response to a particular agent, side effects are the most influential factors when selecting treatment.
Both longitudinal and cross-sectional factors should be considered when selecting an antidepressant for major depression:
• What were the course, duration, and severity of any previous episodes of depression?
• Is there a history of antidepressant response?
• How well was the antidepressant tolerated?
• Is ... Read More
Indications for Use of Antidepressants
Posted By Kelly On Thursday, June 10th 2010 under: Antidepressants Tags: Atypical antidepressants, MAOIs, SNRIs, SSRIs, TCAs
All antidepressants are indicated for the treatment of acute major depressive episodes; there is also evidence for their use in the prevention and relapse and recurrence. In addition, a number of more minor forms of depression may also respond to antidepressant medication, including dysthymic disorder, minor depression, and recurrent brief depression.
All antidepressants appear to treat more than depressive disorders. Particularly consistent have been data showing their utility for anxiety disorders; ... Read More
Antidepressants: Pharmacology
Posted By Kelly On Saturday, June 5th 2010 under: Antidepressants Tags: Atypical antidepressants, MAOIs, SNRIs, SSRIs, TCAs
The use of antidepressants in the treatment of depression remains the best-understood use of these medications; however, there is a growing list of other indications for antidepressants, including panic disorder (PD), obsessive-compulsive disorder (OCD), bulimia and posttraumatic stress disorder (PTSD). Many of these illnesses respond best to combination treatment modalities that include medication and various forms of psychotherapy.
The first antidepressant was the monoamine oxidase inhibitor (MAOI), iproniazid, initially licensed as ... Read More
Case: Antidepressant agents. Questions – Answers
Posted By Kelly On Thursday, June 3rd 2010 under: Pharmacotherapy Tags: Effexor, Prozac, Remeron, Wellbutrin
Questions
Which of the following agents is contraindicated in a patient with epilepsy?
A. Bupropion
B. Fluoxetine
C. Mirtazapine
D. Venlafaxine
The antidepressant action of imipramine is thought to be caused by which of the following?
A. Blockade of prejunctional α2-adrenoceptors
B. Blockade of prejunctional neuronal norepinephrine and serotonin uptake transporters in the CNS
C. Increased numbers of β-adrenoceptors
D. Inhibition of monoamine oxidase
Which of the following antidepressant agents inhibits hepatic microsomal enzymes to cause clinically significant ... Read More
Case: Antidepressant agents. Discussion
Posted By Kelly On Wednesday, June 2nd 2010 under: Pharmacotherapy Tags: Atypical Agents, Selective serotonin reuptake inhibitors (SSRIs), Tricyclic Agents
Class
Drugs used to treat depression are classified as TCAs, atypical heterocyclic (second- and third-generation) agents, SSRIs, and monoamine oxidase inhibitors (MAOIs). Other conditions for which certain antidepressant agents are used include panic disorder, obsessive-compulsive disease (OCD), bipolar affective disorder, chronic pain, and enuresis.
SSRIs are the most extensively prescribed antidepressant agents because, unlike tricyclic and heterocyclic agents, they produce less sedation, have fewer antimuscarinic cholinoreceptor effects, and are safer in overdose. ... Read More
Case: Antidepressant agents
Posted By Kelly On Tuesday, June 1st 2010 under: Pharmacotherapy Tags: Prozac
A 30-year-old woman presents to your office for the evaluation of fatigue. For the past 2 months she has felt run down. She says that she doesn't feel like participating in activities that she previously enjoyed, such as her weekly softball games. She has not been sleeping well and has not had much of an appetite. On questioning, she admits to feeling "down in the dumps" most of the time ... Read More
Amitriptyline
Posted By Kelly On Monday, May 24th 2010 under: Antidepressants
AMITRIPTYLINE (am-ee-TRIP-till-een)
Other Names for this Medication
Elavil, Tryptizol, Laroxyl, Sarotex, Apo-amitriptyline, Bio-amitriptyline, Dom-amitriptyline, PMS-amitriptyline, Novo-triptyn (Brand Names)
Appearance
Tablets: Small blue (10 mg), yellow (25 mg), brown (50 mg), or orange (75 mg) tablets (Apotex brand). Other brands may have different appearances.
Why this Medication is Used
This medication may be used for depression, anxiety or to help you fall asleep. Amitriptyline may also be used to relieve nerve pain.
How do you take this Medication
Depending ... Read More
SSRIs. Forest Laboratories
Posted By Kelly On Friday, May 21st 2010 under: SSRIs Tags: Celexa, Lexapro
Definition of Depression
A diagnosis of major depressive disorder is made if an individual has five or more of the following symptoms during the same two-week period. The symptoms may vary from person to person but often include:
a persistent sad mood
loss of interest or pleasure in activities that were once enjoyed
significant change in appetite or body weight
difficulty sleeping or oversleeping
physical slowing or agitation
loss of energy
feelings of worthlessness or inappropriate guilt
difficulty thinking ... Read More
Hello, everybody, who is interested to be healthy. My name is Kelly. I learnt about depression by my own experience. Now I am ok. Here I want to share my thoughts and ideas how to treat depression symptoms.