Drug lessens severity of premenstrual dysphoria.

Intermittent dosages of fluoxetine (Prozac/Lilly) given during the luteal phase of the menstrual cycle may help women suffering from PMDD (premenstrual dysphoric disorder), studies suggest. Premenstrual dysphoric disorder, a severe variant of premenstrual syndrome, affects 3%-5% of women during their reproductive years, causing depression, anxiety, tension, lability, and irritability. A review of 12 clinical trials led researchers to conclude that, at 20 mg/day, fluoxetine reduces mood symptoms, physical symptoms, and social impairment in women with premenstrual dysphoric disorder and is well-tolerated.

Related posts:

  1. Premenstrual Dysphoric Disorder. Part 3 PMS/PMDD SYMPTOMS Premenstrual syndrome affects as many as 75% of women of reproductive age at some point in their life. However, studies have not defined an exact age-group or time course for this syndrome to occur. But one study suggests that the 25 to...
  2. Premenstrual Dysphoric Disorder. Part 1 SM is a 24-year-old Asian Indian female who presents to her gynecologist with a chief complaint of “severe abdominal pain, breast tenderness, headaches, and weight gain” during her menstrual cycle. She states that her cramps feel like “pins through her stomach.” Her boyfriend states...
  3. Premenstrual Dysphoric Disorder. Part 2 ETIOLOGY AND PATHOPHYSIOLOGY While many studies have focused on the predisposing factors related to premenstrual dysphoric disorder, the relative contributions to this disorder are unclear. Small studies of monozygotic twins have suggested a hereditary link to premenstrual symptoms. Other considerations include a patient’s onset...
  4. Premenstrual Dysphoric Disorder. Part 5. Treatment Once a patient meets the DSM-IV criteria and is diagnosed with premenstrual dysphoric disorder, therapy should be initiated. Consistent with many disorders and disease states, nonpharmacological therapy should be attempted initially. Nonpharmacological Therapy Nonpharmacological therapy consists of dietary modifications, moderate regular exercise, stress...
  5. Premenstrual Dysphoric Disorder. Part 4 CRITERIA FOR DIAGNOSIS An estimated 3% to 8% of women of reproductive age suffer from premenstrual dysphoric disorder. Health care providers have made many attempts to define PMDD and its characteristics to help distinguish it from the common and simple symptoms of PMS. The...