Citalopram (Celexa, Forest Laboratories, Parke-Davis) has been approved by FDA for treatment of depression. A highly selective serotonin reuptake inhibitor, citalopram is the best-selling antidepressant in 13 countries, including eight in Europe. Citalopram has proven effective in treatment of depression in clinical trials involving 23,000 patients and has been used in some 8 million patients in 64 countries where the drug is already approved. Two, six-month, double-blind, placebo-controlled studies indicated that citalopram is significantly more effective than placebo in preventing relapse of depression.
Side effects include nausea, dry mouth, and sleepiness. As with all SSRIs, citalopram should not be taken with monoamine oxidase inhibitors.
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