Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: CP-51974-01; CP-51974-1; Sertralina, hidrocloruro de BAN: Sertraline Hydrochloride [BANM] USAN: Sertraline Hydrochloride INN: Sertraline Hydrochloride [rINNM (en)] INN: Hidrocloruro de sertralina [rINNM (es)] INN: Sertraline, Chlorhydrate de [rINNM (fr)] INN: Sertralini Hydrochloridum [rINNM (la)] INN: Сертралина Гидрохлорид [rINNM (ru)] Chemical name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl(methyl)amine hydrochloride Molecular formula: C17H17Cl2N,HCl =342.7 CAS: 79617-96-2 (sertraline); 79559-97-0 (sertraline hydrochloride) ATC code: N06AB06 Note. The following terms have been used as ‘street names’ or slang names for various forms of sertraline: Z’s Zloft Zoomers. Pharmacopoeias. In Europe. European Pharmacopoeia, 6th ed. (Sertraline Hydrochlonde). A white or almost white, crystalline powder, ft exhibits polymorphism. Slightly soluble in water freely soluble in anhydrous alcohol Read more [...]
Depression Symptoms Treatment
Archive for December, 2010
General Principles of Pharmacologic Intervention A thorough history, physical examination, and basic laboratory studies are important to fully evaluate the patient and rule out medical and medication-related causes of insomnia and depression. Additionally, the selection of the appropriate antidepressant medication (selective serotonin reuptake inhibitors, tricyclic antidepressants [TCAs], monoamine oxidase inhibitors, or atypical antidepressants), adequate dosages, and a sufficient trial period are imperative in the treatment of depression in the elderly. In seniors, an adequate antidepressant trial is longer than that for younger adults, with a complete response often seen after six to 12 weeks. Nuances related to medication therapy in the geriatric population should be clearly expressed by pharmacists in recommendations and educational communications. The impact of aging and medical conditions associated with aging on the pharmacokinetic profile of a medication and the increased risk of associated side effects must be understood with regard to geriatric dosage guidelines, disease-drug contraindications Read more [...]
Drug Nomenclature Synonyms: FCE-20124 (reboxetine or reboxetine mesilate); PNU-155950E; Reboxetina, mesilato de; Reboxetine Mesylate BAN: Reboxetine Mesilate [BANM] USAN: Reboxetine Mesylate INN: Reboxetine Mesilate [rINNM (en)] INN: Mesilato de reboxetina [rINNM (es)] INN: Réboxétine, Mésilate de [rINNM (fr)] INN: Reboxetini Mesilas [rINNM (la)] INN: Ребоксетина Мезилат [rINNM (ru)] Chemical name: (±)-(2RS)-2-[(αRS)-α(2-Ethoxyphenoxy)benzyl]morpholine methanesulphonate Molecular formula: C19H23NO3,CH4O3S =409.5 CAS: 71620-89-8; 98769-81-4 (both reboxetine); 98769-82-5; 98769-84-7 (both reboxetine mesilate) ATC code: N06AX18 Adverse Effects Adverse effects most commonly seen with reboxetine include insomnia, dry mouth, constipation, and increased sweating. Disturbance of visual accommodation, loss of appetite, vertigo, tachycardia, palpitations, vasodilatation, orthostatic hypotension, urinary hesitancy or retention (mainly in men), and erectile dysfunction including ejaculatory delay are also reported as being common adverse reactions. There have been reports of allergic Read more [...]
Drug Nomenclature Synonyms: MK-240; Protriptilina, hidrocloruro de BAN: Protriptyline Hydrochloride [BANM] USAN: Protriptyline Hydrochloride INN: Protriptyline Hydrochloride [rINNM (en)] INN: Hidrocloruro de protriptilina [rINNM (es)] INN: Protriptyline, Chlorhydrate de [rINNM (fr)] INN: Protriptylini Hydrochloridum [rINNM (la)] INN: Протриптилина Гидрохлорид [rINNM (ru)] Chemical name: 3-(5H-Dibenzo[a,d]cyclohept-5-enyl)propyl(methyl)amine hydrochloride Molecular formula: C19H21N,HCl =299.8 CAS: 438-60-8 (protriptyline); 1225-55-4 (protriptyline hydrochloride) ATC code: N06AA11 Read code: y025a Pharmacopoeias. In British and US. BP 2008 (Protriptyline Hydrochloride). A white to yellowish-white, odourless or almost odourless, powder. Freely soluble in water, in alcohol, and in chloroform practically insoluble in ether A 1% solution in water has a pH of 5.0 to 6.5. The United States Pharmacopeia 31, 2008 (Protriptyline Hydrochloride). A white to yellowish powder. Is odourless or has not more than a slight odour. Soluble 1 in 2 of water, 1 in 3.5 of alcohol, and Read more [...]
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: 38489; Nortriptilin-hidroklorid; Nortriptilina, hidrocloruro de; Nortriptilino hidrochloridas; Nortriptyliinihydrokloridi; Nortriptylin-hydrochlorid; Nortriptylinhydroklorid; Nortriptylini Hydrochloridum BAN: Nortriptyline Hydrochloride [BANM] USAN: Nortriptyline Hydrochloride INN: Nortriptyline Hydrochloride [rINNM (en)] INN: Hidrocloruro de nortriptilina [rINNM (es)] INN: Nortriptyline, Chlorhydrate de [rINNM (fr)] INN: Nortriptylini Hydrochloridum [rINNM (la)] INN: Нортриптилина Гидрохлорид [rINNM (ru)] Chemical name: 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(methyl)amine hydrochloride Molecular formula: C19H21N,HCl =299.8 CAS: 72-69-5 (nortriptyline); 894-71-3 (nortriptyline hydrochloride) ATC code: N06AA10 Read code: y00VT [Enuresis] Pharmacopoeias. In Europe, Japan, and US. European Pharmacopoeia, 6th ed. (Nortriptyline Hydrochloride). A white or almost white powder. Sparingly Read more [...]
Drug Nomenclature Synonyms: DU-23000; Fluvoksamiinimaleaatti; Fluvoxamina, maleato de; Fluvoxamini Maleas; Fluvoxaminmaleat BAN: Fluvoxamine Maleate [BANM] USAN: Fluvoxamine Maleate INN: Fluvoxamine Maleate [rINNM (en)] INN: Maleato de fluvoxamina [rINNM (es)] INN: Fluvoxamine, Maléate de [rINNM (fr)] INN: Fluvoxamini Maleas [rINNM (la)] INN: Флувоксамина Малеат [rINNM (ru)] Chemical name: (E)-5-Methoxy-4´-trifluoromethylvalerophenone O-2-aminoethyloxime maleate Molecular formula: C15H21F3N2O2,C4H4O4 =434.4 CAS: 54739-18-3 (fluvoxamine); 61718-82-9 (fluvoxamine maleate) ATC code: N06AB08 Read code: y026Z Pharmacopoeias. In Europe and US. European Pharmacopoeia, 6th ed. (Fluvoxamine Maleate). A white or almost white, crystalline powder. Sparingly soluble in water freely soluble in alcohol and in methyl alcohol. The United States Pharmacopeia 31, 2008 (Fluvoxamine Maleate). A white to off-white, crystalline powder. Sparingly soluble in water freely soluble in alcohol and in chloroform practically insoluble in solvent ether. Protect from light. Adverse Effects, Treatment, and Read more [...]
Drug Approvals (British Approved Name, US Adopted Name, rINN) INNs in other languages (French, Latin, and Spanish): Synonyms: BRL-29060; FG-7051; Paroksetiini; Paroxetin; Paroxetinum BAN: Paroxetine USAN: Paroxetine INN: Paroxetine [rINN (en)] INN: Paroxetina [rINN (es)] INN: Paroxétine [rINN (fr)] INN: Paroxetinum [rINN (la)] INN: Пароксетин [rINN (ru)] Chemical name: (-)-trans-5-(4-p-Fluorophenyl-3-piperidylmethoxy)-1,3-benzodioxole Molecular formula: C19H20FNO3 =329.4 CAS: 61869-08-7 ATC code: N06AB05 Paroxetine Hydrochloride Drug Approvals (British Approved Name Modified, rINNM) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: BRL-29060A; Paroksetiinihydrokloridihemihydraatti; Paroksetino hidrochloridas hemihidratas; Paroxetin hydrochlorid; Paroxetina, hidrocloruro de; Paroxetine Hydrochloride Hemihydrate; Paroxetinhydrokloridhemihydrat; Paroxetini Hydrochloridum; Paroxetini Hydrochloridum Hemihydricum BAN: Paroxetine Hydrochloride [BANM] INN: Paroxetine Hydrochloride [rINNM (en)] INN: Hidrocloruro de paroxetina [rINNM (es)] INN: Read more [...]
Drug Approvals (British Approved Name Modified, US Adopted Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: AF-1161; Trazodona, hidrocloruro de BAN: Trazodone Hydrochloride [BANM] USAN: Trazodone Hydrochloride INN: Trazodone Hydrochloride [rINNM (en)] INN: Hidrocloruro de trazodona [rINNM (es)] INN: Trazodone, Chlorhydrate de [rINNM (fr)] INN: Trazodoni Hydrochloridum [rINNM (la)] INN: Тразодона Гидрохлорид [rINNM (ru)] Chemical name: 2-[3-(4-m-Chlorophenylpiperazin-1-yl)propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride Molecular formula: C19H22ClN5O,HCl =408.3 CAS: 19794-93-5 (trazodone); 25332-39-2 (trazodone hydrochloride) ATC code: N06AX05 Read code: y025f Note. The following terms have been used as ‘street names’ (see p.vi) or slang names for various forms of trazodone hydrochloride: Sleepeasy. Pharmacopoeias. In British and US. BP 2008 (Trazodone Hydrochloride). A white or almost white crystalline powder. Soluble in water sparingly soluble in alcohol practically insoluble in ether. A 1% solution Read more [...]