Archives for March, 2010
Management of treatment-resistant depression: strategies for treatment
Posted By Kelly On Saturday, March 6th 2010 under: Management Tags: Antidepressants, clomipramine-tryptophan-trd, Depression, Treatment
Common strategies for treatment resistance.
Electroconvulsive therapy
An important and effective treatment for depression, electroconvulsive therapy (ECT) is effective in about 90% of cases of major depression. The success rate drops when it is used for drug-refractory cases. Using ECT depends on patient-related factors: it clearly is the treatment of choice for depression with psychomotor slowing, stupor, psychotic symptoms, or depression requiring rapid response because of suicidal risk or malnutrition. Use of ... Read More
Management of treatment-resistant depression: Switching antidepressants
Posted By Kelly On Thursday, March 4th 2010 under: Management Tags: Antidepressants, Depression, depression-symptoms-chart, Treatment
If lithium augmentation is ineffective, it should be discontinued and the antidepressant changed (Table 5). A lack of response to one of the newer agents in a class, such as the selective serotonin reuptake inhibitors (SSRIs), does not predict lack of response to others in that class. If the first drug used was a reversible inhibitors of monoamine oxidase A (RIMA) with only one drug in the class, the ... Read More
Management of treatment-resistant depression (TRD)
Posted By Kelly On Tuesday, March 2nd 2010 under: Management Tags: Antidepressants, Depression, lithium-augmentation-success, lithium-success-in-treating-depression, Treatment
Major depression is best managed through a treatment algorithm. The more resistant to treatment a patient's illness is, the further treatment proceeds through the steps. As each trial of therapy is deemed ineffective, diagnosis should be reviewed and physical and psychosocial factors reassessed before making a decision about the next step. Psychotherapy is an essential accompaniment to any form of somatic treatment. Supportive psychotherapy offers reassurance and time for patients ... Read More